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O1257

Sigma-Aldrich

油酸-水溶性

powder, BioReagent, suitable for cell culture

别名:

油酸-环糊精复合物

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About This Item

MDL號碼:
MFCD00064242
分類程式碼代碼:
12352211
PubChem物質ID:
24897936
NACRES:
NA.75

生物源

synthetic (organic)

品質等級

200

產品線

BioReagent

形狀

powder

成份

Oleic acid, ~30 mg/g (balance methyl-β-cyclodextrin)

技術

cell culture | mammalian: suitable

溶解度

H2O: 50 mg/mL, clear to slightly hazy

儲存溫度

−20°C

SMILES 字串

CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-

InChI 密鑰

ZQPPMHVWECSIRJ-KTKRTIGZSA-N

基因資訊

human ... SOAT1(6646) , SOAT2(8435)

相关类别

應用

十八烯酸水溶液可用于：
  • 制备用于细胞处理的FFA（游离脂肪酸）混合物
  • 研究其对L6肌细胞中溶质载体家族2成员4 (SLC2A4)/GLUT4表达的影响，并用作潜在的转录调控因子
  • 制备脂肪培养基，用于诱导原代人肝细胞的体外脂肪变性

其他說明

甲基-β-环葡聚糖结合改善了油酸在培养基中的溶解度和运输。

相關產品

产品编号
说明
价格

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000406758
0000300019
0000360530
0000360530
0000406758

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Oleic and linoleic fatty acids downregulate Slc2a4/GLUT4 expression via NFKB and SREBP1 in skeletal muscle cells
Poletto A C, et al.
Molecular and Cellular Endocrinology, 401(12), 65-72 (2015)
A20 attenuates FFAs-induced lipid accumulation in nonalcoholic steatohepatitis
Ai L, et al.
International Journal of Biological Sciences, 11(12), 1436-1436 (2015)
Shuo Li et al.
International journal of biological sciences, 17(15), 4165-4175 (2021-11-23)
Background: Inflammation and apoptosis play a crucial role in the progression of nonalcoholic steatohepatitis (NASH). Suppressor of cytokine signaling 2 (SOCS2) is one of classic negative regulators of cytokine signaling, which has recently been described as anti-inflammatory mediators. However, the
Pu Sun et al.
Journal for immunotherapy of cancer, 9(8) (2021-08-11)
The phosphatidylinositol 3-kinase (PI3K) is frequently hyperactivated in cancer and plays important roles in both malignant and immune cells. The effect of PI3Kα inhibitors on the tumor microenvironment (TME) remains largely unknown. Here, we investigated the modulation of the TME
Kangpeng Jin et al.
Theranostics, 10(12), 5290-5304 (2020-05-07)
Rationale: Inflammation plays a crucial role in the progression of nonalcoholic steatohepatitis (NASH). Protein tyrosine phosphatase receptor type O truncated isoform (PTPROt) is an integral membrane protein that has been identified in osteoclasts, macrophages, and B lymphocytes. However, its relationship
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油酸在细胞培养中的应用

不饱和脂肪酸、油酸和其他细胞培养成分如何影响无血清、无蛋白细胞培养系统（用于生物制造包括单克隆抗体在内的异源蛋白）的性能。

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