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Merck
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N144

Sigma-Aldrich

尼群地平

>95%, powder

别名:

1,4-二氢-2,6-二甲基-4-(3-硝基苯)-3,5-吡啶二羧酸乙基甲酯

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About This Item

经验公式（希尔记法）:
C18H20N2O6
CAS号:
39562-70-4
分子量:
360.36
EC 号:
254-513-1
MDL编号:
MFCD00082255
UNSPSC代码:
12352200
PubChem化学物质编号:
24277857
NACRES:
NA.77

方案

>95%

表单

powder

颜色

yellow to green

溶解性

methanol: 15 mg/mL
DMSO: 17.5 mg/mL
H2O: insoluble

SMILES字符串

CCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OC

InChI

1S/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,16,19H,5H2,1-4H3

InChI key

PVHUJELLJLJGLN-UHFFFAOYSA-N

基因信息

human ... ADORA3(140) , CACNG1(786) , KCNH1(3756) , TTR(7276)
rat ... Adora1(29290) , Adora2a(25369)

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生化/生理作用

Ca2+ channel blocker; anti-hypertensive.

储存分类代码

11 - Combustible Solids

WGK

WGK 1

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
028F08941
038H4745

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Jian X Wu et al.
International journal of pharmaceutics, 433(1-2), 60-70 (2012-05-09)
This study focuses on the development of an automated image analysis method to extract information on nucleation and crystal growth from polarized light micrographs. Using the developed image analysis method, four parameters related to nucleation and crystal growth could be
Annik Bergeron et al.
Bioanalysis, 4(8), 897-908 (2012-04-27)
In the past several years, the impact of changing counter ions while keeping the same anticoagulant in bioanalytical LC-MS/MS methods has become a highly discussed topic. In order to confirm that there is no impact from counter ions, matrix effect
Felix Steger et al.
Radiation oncology (London, England), 7, 212-212 (2012-12-18)
5-Fluorouracil (5-FU) is an antimetabolite, which is frequently used as chemotherapeutic agent for combined chemoradiotherapy. The purpose of this study was to present the clinical course of three patients who developed severe cardiac toxicity by 5-FU and to give a
Xiaowei Shi et al.
Journal of pharmaceutical and biomedical analysis, 56(5), 1101-1105 (2011-09-03)
A novel and sensitive method utilizing high performance liquid chromatography coupled with electrospray ionization source tandem mass spectrometry (LC-ESI-MS(3)) was developed for the first time in order to analyze nitrendipine in human plasma samples. Human plasma samples were prepared by
Peng Quan et al.
AAPS PharmSciTech, 12(4), 1136-1143 (2011-09-06)
The present investigation was undertaken with the objective of developing a solid formulation containing nitrendipine nanocrystals for oral delivery. Nitrendipine nanocrystals were prepared using a tandem precipitation-homogenization process. Then, spray drying, a cost-effective method very popular in industrial situations, was
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