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Merck

N0761

Sigma-Aldrich

烟酸

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%

别名:

3-吡啶甲酸, 吡啶-3-羧酸, 尼亚生, 抗糙皮病因子, 维生素 B3

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About This Item

经验公式(希尔记法):
C6H5NO2
CAS号:
分子量:
123.11
Beilstein:
109591
EC號碼:
MDL號碼:
分類程式碼代碼:
12352207
PubChem物質ID:
NACRES:
NA.71

產品線

BioReagent

化驗

≥98%

形狀

powder

分子量

Mw 123.11 g/mol

技術

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

顏色

white to off-white

pH值

3.4 (20 °C, 10 g/L)

mp

236-239 °C (lit.)

溶解度

1 M NaOH: soluble 50 mg/mL, clear, colorless to very faintly yellow

密度

1.473 g/cm3 at 25 °C

應用

agriculture

SMILES 字串

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI 密鑰

PVNIIMVLHYAWGP-UHFFFAOYSA-N

基因資訊

human ... CYP1A2(1544)
rat ... Chrnb2(54239)

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象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

379.4 °F - closed cup

閃點(°C)

193 °C - closed cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Sorin Tunaru et al.
Nature medicine, 9(3), 352-355 (2003-02-04)
Nicotinic acid (niacin), a vitamin of the B complex, has been used for almost 50 years as a lipid-lowering drug. The pharmacological effect of nicotinic acid requires doses that are much higher than those provided by a normal diet. Its
Koon K Teo et al.
Stroke, 44(10), 2688-2693 (2013-07-25)
In Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcomes (AIM-HIGH) trial, addition of extended-release niacin (ERN) to simvastatin in participants with established cardiovascular disease, low high-density lipoprotein cholesterol, and high triglycerides had no incremental
Beat Müller et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 20(2), 181-195 (2003-10-11)
A novel methodology for establishing a pharmacological dose-effect relationship of methyl nicotinate, hexyl nicotinate and nicotinic acid acting as peripheral vasodilators in the skin following topical application is investigated. This methodology involves the estimation of the unbound drug concentration in
Paul M Lavigne et al.
Journal of the American College of Cardiology, 61(4), 440-446 (2012-12-26)
This study sought to assess the efficacy of niacin for reducing cardiovascular disease (CVD) events, as indicated by the aggregate body of clinical trial evidence including data from the recently published AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High
John R Guyton et al.
Journal of the American College of Cardiology, 62(17), 1580-1584 (2013-08-07)
This study sought to examine the relationship between niacin treatment, lipoproteins, and cardiovascular (CV) outcomes in this secondary analysis of the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes) trial. During a

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