MSST0040

SILu^™Lite IFNG Interferon Gamma human

recombinant, expressed in HEK 293 cells, MS Protein Standard

• 别名: IFNγ, IFN-gamma, Immune interferon, Immuneinterferon
• UNSPSC代码: 23201100
• NACRES: NA.12

属性

• 生物来源: human
• 质量水平: 200
• 重组: expressed in HEK 293 cells
• 方案: ≥98% (SDS-PAGE)
• 表单: lyophilized powder
• 效能: ≥98% Heavy amino acids incorporation efficiency by MS
• 分子量: calculated mol wt 17 kDa
• 技术: mass spectrometry (MS): suitable
• 适用性: suitable for mass spectrometry (internal calibrator)
• UniProt登记号: P01579
• 储存温度: −20°C
• 基因信息: human ... IFNG(3458)

说明

一般描述

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. IFNγ is secreted by T helper cells (specifically, Th1 cells), cytotoxic T cells (TC cells) and Natural killer (NK) cells. When combined with other inflammatory cytokines, evaluating the levels of IFNγ can be used as a diagnostic tool in patients with breast cancer or benign prostatic hyperplasia. A recent study evaluated the effect of a cancer vaccine given to patients with colorectal cancer, on the levels of plasma pro-inflammatory cytokines (including IFN-γ). The study concluded that patients achieving stable disease showed increasing levels of plasma inflammatory cytokines.

免疫原

QDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRG

生化/生理作用

SILu^™Lite IFNG is a recombinant human protein expressed in human 293 cells. It is a homodimer consisting of 138 amino acids Expressed in human 293 cells, with a calculated molecular mass of 17 kDa. SILu Lite IFNG is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.

外形

Lyophilized from a solution of phosphate buffered saline.

法律信息

SILu is a trademark of Sigma-Aldrich Co. LLC

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 2
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable