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Merck

MAK033

Sigma-Aldrich

二磷酸腺苷(ADP)检测试剂盒(比色法/荧光法)

sufficient for 100 colorimetric or fluorometric tests

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About This Item

UNSPSC代码:
12352200
NACRES:
NA.84

用途

sufficient for 100 colorimetric or fluorometric tests

检测方法

colorimetric
fluorometric

储存温度

−20°C

一般描述

现在我们可提供全新的ADP检测试剂盒MAK518!腺苷二磷酸(ADP)是一种核苷二磷酸,在能量转移反应中起关键作用。ADP是在ATP酶的作用下,由腺苷三磷酸 (ATP)生产。ADP也在血小板的功能中起关键作用。ADP储存在血小板致密颗粒(platelet-dense granule)中,通过血小板的活化释放,在这一过程中ADP作用于嘌呤受体,从而介导胞内信号传导和血小板聚集。ADP是血栓形成和止血的关键激动剂。

特点和优势

兼容高通量操作系统。

适用性

适用于测定多种生物样本中的 ADP,包括细胞和组织裂解物

原理

在该试验中,通过偶联酶反应测定 ADP(二磷酸腺苷)浓度,得到比色 (570 nm)/荧光 (λ ex = 535/λ em = 587 nm) 乘积,与存在的 ADP 成比例。

替代产品

产品编号
说明
价格

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

10 - Combustible liquids

闪点(°F)

188.6 °F - closed cup

闪点(°C)

87 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs.
Foster C J, et al.
The Journal of Clinical Investigation, 107(12), 1591-1598 (2001)
ADP is not an agonist at P2X1 receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets.
Mahaut-Smith M P, et al.
British Journal of Pharmacology, 131(1), 108-114 (2000)
Multinuclear magnetic resonance spectroscopy studies of brain purines in major depression.
Renshaw P F, et al.
The American Journal of Psychiatry, 158(12), 2048-2055 (2001)
Ana Luisa Palacios-Acedo et al.
Frontiers in oncology, 11, 704945-704945 (2021-10-01)
Platelet function can be modified by cancer cells to support tumor growth, causing alterations in the delicate hemostatic equilibrium. Cancer-cell and platelet interactions are one of the main pillars of Trousseau's syndrome: a paraneoplastic syndrome with recurring and migrating episodes
Jianmin Zhang et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 39(9), 1836-1848 (2018-04-17)
Neuronal preconditioning in vitro or in vivo with a stressful but non-lethal stimulus leads to new protein expression that mediates a profound neuroprotection against glutamate excitotoxicity and experimental stroke. The proteins that mediate neuroprotection are relatively unknown and under discovery.

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