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Merck

M7504

Sigma-Aldrich

甘露聚糖 来源于酿酒酵母

prepared by alkaline extraction

别名:

D-Mannan

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352201
NACRES:
NA.25

生物源

bakers yeast (whole cell)

形狀

powder

光學活性

[α]/D 73 to 89 °, c = 1% (w/v) in water

雜質

<1.0% Low molecular weight saccharides (TLC)

顏色

beige

溶解度

water: ~50 g/L

正離子痕跡

Na: <2%

儲存溫度

2-8°C

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一般說明

甘露聚糖是酵母细胞壁的主要多糖成分,在自然中广泛存在,包括植物、细菌、酵母等生物。作为高度分支的多糖分子,α-1,6骨架连接α-1,2-和α-1,3-键两种甘露糖侧链。

應用

本品(酿酒酵母来源甘露聚糖)已用于包被微孔板,通过甘露聚糖结合酶联免疫吸附试验(ELISA)定量测定甘露糖结合凝集素(MBL)。
来自酿酒酵母(Saccharomyces cerevisiae)的甘露聚糖已被用于评估人单核细胞和肺泡巨噬细胞对禽分枝杆菌复合物的非调理吸收。 它也被用于研究来自于Croccus sativum的新的凝集素。

生化/生理作用

甘露聚糖具有抗增殖、抗氧化和免疫调节等多种生物特性。可用作硬化剂组分和乳化稳定剂。甘露聚糖也参与病原体黏附抑制、细菌生长调节和免疫应答增强。

準備報告

使用Haworth的方法进行配制。

其他說明

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Y Oda et al.
Biological & pharmaceutical bulletin, 16(10), 978-981 (1993-10-01)
Four isolectins were isolated from bulbs of Croccus sativum (saffron), using affinity chromatography on mannan-Sepharose 4B, gel filtration and ion-exchange column chromatography in the presence of 8 M urea. The relative molecular masses of these lectins were determined by gel
Michael L Patnode et al.
Cell, 179(1), 59-73 (2019-09-21)
Development of microbiota-directed foods (MDFs) that selectively increase the abundance of beneficial human gut microbes, and their expressed functions, requires knowledge of both the bioactive components of MDFs and the mechanisms underlying microbe-microbe interactions. Here, gnotobiotic mice were colonized with
Polysaccharides. Part XXIV. Yeast mannan.
Haworth, W.N., et al.
Journal of the Chemical Society, 784-791 (1937)
J A Roecklein et al.
The Journal of laboratory and clinical medicine, 119(6), 772-781 (1992-06-11)
The uptake of Mycobacterium avium complex (MAC) microorganisms by human peripheral blood monocytes (PBMs) and alveolar macrophages (AMs) is not well understood. We have previously shown, under opsonic conditions, that humoral factors are important in mediating the uptake of MAC
Geelsu Hwang et al.
PLoS pathogens, 13(6), e1006407-e1006407 (2017-06-16)
Candida albicans is frequently detected with heavy infection by Streptococcus mutans in plaque-biofilms from children with early-childhood caries (ECC). This cross-kingdom biofilm contains an extensive matrix of extracellular α-glucans that is produced by an exoenzyme (GtfB) secreted by S. mutans.

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