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Merck

M4670

Sigma-Aldrich

D -甘露糖胺 盐酸盐

≥98% (HPLC)

别名:

2-氨基-2-脱氧-D-甘露糖 盐酸盐

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About This Item

经验公式(希尔记法):
C6H13NO5 · HCl
CAS号:
分子量:
215.63
Beilstein:
3914860
EC號碼:
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.25

生物源

crab (shell)
shrimp shells

化驗

≥98% (HPLC)

形狀

powder

技術

HPLC: suitable

顏色

white

mp

168 °C (dec.) (lit.)

溶解度

water: 50 mg/mL, clear, colorless to faintly yellow

儲存溫度

2-8°C

SMILES 字串

Cl[H].N[C@@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3+,4-,5-,6?;/m1./s1

InChI 密鑰

QKPLRMLTKYXDST-OHXGPSCHSA-N

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應用

D-甘露糖胺盐酸盐可用于合成非天然甘露糖类似物,用于在细胞表面唾液酸上表达硫醇。 已用于研究探讨 N-乙酰-β 的合成及高通量筛选-氨基己糖苷酶抑制剂文库靶向骨关节炎。

其他說明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Srinivasa-Gopalan Sampathkumar et al.
Nature protocols, 1(5), 2377-2385 (2007-04-05)
The sialic acid biosynthetic pathway in mammalian cells utilizes N-acetyl-D-mannosamine (ManNAc) as a natural metabolic precursor and has the remarkable ability to biosynthetically process non-natural ManNAc analogs. Herein, we describe a recipe-style protocol for the synthesis of the novel peracetylated
Junjie Liu et al.
The Journal of organic chemistry, 69(19), 6273-6283 (2004-09-11)
C1 Nitrogen iminocyclitols are potent inhibitors of N-acetyl-beta-hexosaminidases. Given hexosaminidases' important roles in osteoarthritis, we developed two straightforward and efficient syntheses of C1 nitrogen iminocyclitols from two readily available starting materials, D-mannosamine hydrochloride and the microbial oxidation product of fructose.
Tal Gefen et al.
Vaccine, 28(51), 8197-8202 (2010-09-30)
Passive immunization with cross-species antibodies triggers the patient's immune response, thereby preventing repeated treatment. Mannosamine-biotin adduct (MBA) has been described as a masking agent for immunogenic reduction and here, the immunogenicity and biological activity of MBA-coated horse anti-viper venom (hsIgG)
Christopher Brigham et al.
Journal of bacteriology, 191(11), 3629-3638 (2009-03-24)
We characterized the nanLET operon in Bacteroides fragilis, whose products are required for the utilization of the sialic acid N-acetyl neuraminic acid (NANA) as a carbon and energy source. The first gene of the operon is nanL, which codes for
Filippo Bonaccorsi et al.
Carbohydrate research, 344(12), 1442-1448 (2009-05-27)
The recently described [Attolino, E.; Bonaccorsi, F.; Catelani, G.; D'Andrea, F. Carbohydr. Res. 2008, 343, 2545-2556.] beta-D-MaNAcp-(1-->4)-beta-D-Glcp thiophenyl glycosyl donor 3 was used in alpha-glycosylation reactions of OH-2 and OH-3 of the suitably protected p-MeO-benzyl alpha-l-rhamnopyranoside acceptors 7 and 8.

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