儲存溫度
2-8°C
SMILES 字串
Cc1nnc2ccc(nn12)-c3cccc(c3)C(F)(F)F
基因資訊
human ... BZRAP1(9256) , GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA5(2558) , GABRA6(2559) , GABRG2(2566)
生化／生理作用
Selective agonist at the BZI benzodiazepine receptor.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
M C Gravielle et al.
Neuroreport, 6(15), 2013-2016 (1995-10-23)
The developmental time-course of type I and type II benzodiazepine receptors in the chick optic lobe was determined using a triazolopyridazine, CL 218872. At embryonic day 13 most of the binding sites corresponded to type II (98.23%), while type I
A Hendrickson et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 12(4), 299-314 (1994-06-01)
The expression of subtypes of the GABA-A/benzodiazepine receptor complex has been studied during pre- and postnatal development of Macaca monkey visual cortex using complementary radioligand and immunocytochemical labeling. Type I benzodiazepine receptors were labeled directly by [3H]zolpidem. Type II receptors
K A Wafford et al.
Molecular pharmacology, 44(2), 437-442 (1993-08-01)
The effect of benzodiazepines on the activity of gamma-aminobutyric acid (GABA)A receptors has been shown to be influenced by different alpha subunits and can also be affected by the presence of different gamma subunits. Previous studies have shown that receptors
T Yakushiji et al.
British journal of pharmacology, 109(3), 819-825 (1993-07-01)
1. The effects of benzodiazepine receptor (BZR) partial agonists, Y-23684 and CL218,872, were compared with its full agonist, diazepam, on gamma-aminobutyric acid (GABA)-induced Cl- current (ICl) in acutely dissociated rat cerebral cortex (CTX), cerebellar Purkinje (CPJ) and spinal ventral horn
D Ruano et al.
European journal of pharmacology, 246(1), 81-87 (1993-06-15)
We have investigated the possible modifications of the pharmacological properties of Type I and Type II benzodiazepine binding sites of the gamma-aminobutyric acidA (GABAA) receptor complex in cortical membranes from 3- and 24-month-old Wistar or Fischer rats. No major changes
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