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Merck
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文件

L6638

Sigma-Aldrich

单磷酰脂质A 来源于大肠杆菌 F583（Rd 突变体）

lyophilized powder

别名:

E. coli Monophosphoryl Lipid A

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About This Item

MDL號碼:
MFCD00131511
分類程式碼代碼:
12352211
NACRES:
NA.25

生物源

Escherichia coli (F583 Rd mutant)

品質等級

200

形狀

lyophilized powder

雜質

<0.2% Ketodeoxyoctonate (KDO)

運輸包裝

ambient

儲存溫度

2-8°C

相关类别

生化／生理作用

脂质A分子组成了由革兰氏阴性菌所产生的内毒素的脂膜锚定核心成分。脂质A分子可诱导免疫反应。结构上，脂质A分子由两个物种依赖性、脂肪酰基链数、同一性和磷酸化程度均不同的葡糖胺单元所组成。
来自大肠杆菌F583的单磷酰基脂质A可用于对不同LPA分子和类似物内特定结构的抗原性进行比较性评估。
脂质A具有免疫刺激佐剂活性，包括巨噬细胞、T细胞和B细胞活化。研究表明脂质A对于Th2有比Th1更大的刺激。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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