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Merck
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主要文件

L3908

Sigma-Aldrich

β-乳球蛋白 来源于牛奶

≥90% (PAGE), lyophilized powder

别名:

βLg, BLG, Bos d 5, beta-lactoglobulin

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About This Item

CAS号:
EC 号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.61

生物来源

bovine milk

方案

≥90% (PAGE)

表单

lyophilized powder

技术

ELISA: suitable

UniProt登记号

储存温度

2-8°C

基因信息

bovine ... LGB(280838)

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一般描述

来自奶牛的牛奶含有β-乳球蛋白(BLG)。它天然存在许多遗传变异体,最普遍的牛变异体是BLG A和BLG B。

应用

β-乳球蛋白被用于细胞学检测,以诊断肠易激综合征患者的食物超敏反应。

生化/生理作用

βLg是脂质运载蛋白家族的成员,它是由162个氨基酸组成的小分子蛋白,分子量约为18,400Da。它具有由八条链组成的β桶状结构(A-H链),桶外存在一个具有三个转角的a螺旋和第九条β链(I链),其形成二聚体形成界面的一部分。

其他说明

含 β-乳球蛋白 A 和 B,可通过色谱法分离。

质量

可能不含叶酸结合蛋白;不推荐用于叶酸分析。

制备说明

色谱纯化产品

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sirpa Jylhä et al.
Journal of immunological methods, 350(1-2), 63-70 (2009-08-04)
Cow's milk allergy (CMA) is a common food allergy, especially among infants and young children. Approximately 85% of milk-allergic children outgrow their allergy by the age of three but the remaining 15% remain allergic. Bovine beta-lactoglobulin (BLG) is one of
Junzhen Zhong et al.
Food chemistry, 278, 491-496 (2018-12-26)
Previous work indicated that conformational changes of β-lactoglobulin (β-LG) induced by dynamic high pressure microfluidization (DHPM) was related to the increase of antigenicity. In this study, β-LG glycated with 1-kestose and combined with DHPM decreased the antigenicity of β-LG. The
Jonathan Vaneyck et al.
The Journal of biological chemistry, 296, 100358-100358 (2021-02-05)
The aggregation of the protein α-synuclein (aSyn) into amyloid fibrils in the human brain is associated with the development of several neurodegenerative diseases, including Parkinson's disease. The previously observed prion-like spreading of aSyn aggregation throughout the brain and the finding
Lena Wartosch et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(12), 4056-4068 (2009-08-08)
Mutations in either ClC-7, a late endosomal/lysosomal member of the CLC family of chloride channels and transporters, or in its beta-subunit Ostm1 cause osteopetrosis and lysosomal storage disease in mice and humans. The severe phenotype of mice globally deleted for
Tilman Barz et al.
Journal of chromatography. A, 1217(26), 4267-4277 (2010-05-07)
In this work, parameters of the steric mass-formalism SMA are optimally ascertained for a reliable determination of the adsorption isotherms of beta-lactoglobulin A and B under non-isocratic conditions. For this purpose, static batch experiments are used in contrast to the

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