所有图片(1)
About This Item
经验公式（希尔记法）:
C20H38N6O4 · HCl
CAS号:
分子量:
463.01
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77
推荐产品
product name
亮肽素 盐酸盐, microbial, ≥70% (HPLC)
生物源
microbial
品質等級
化驗
≥70% (HPLC)
形狀
powder
溶解度
water: 50 mg/mL, clear, colorless to yellow
儲存溫度
−20°C
SMILES 字串
Cl.CC(C)CC(NC(C)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(N)=N)C=O
InChI
1S/C20H38N6O4.ClH/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);1H
InChI 密鑰
OQQYPQNFLLAILR-UHFFFAOYSA-N
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生化／生理作用
丝氨酸和半胱氨酸蛋白酶抑制剂。抑制纤溶酶、胰蛋白酶、木瓜蛋白酶、钙蛋白酶和组织蛋白酶 B。不抑制胃蛋白酶、组织蛋白酶 A 和 D、凝血酶或 α-糜蛋白酶。有效浓度 10-100 μM。已有许多研究使用亮肽素预防由声过度刺激或耳毒性抗生素庆大霉素引起的听力丧失。（耳蜗毛细胞的丢失被认为是由钙蛋白酶介导的。）
分析報告
Leupeptin gives multiple peaks on HPLC because of the formation of tautomeric isomers in solution. Majority of contaminating peptide is racemized leupeptin.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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