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一般描述
ETT activator is an activator solution containing 5-(Ethylthio)-1H-tetrazole – a powerful activator – in acetonitrile. It is mixed with phosphoramidite during the extension step in which it reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.
应用
ETT activator has been used in the fast and low-cost synthesis of photolithographic DNA microarrays.
警示用语:
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 3
闪点(°F)
35.6 °F
闪点(°C)
2 °C
其他客户在看
Matej Sack et al.
Journal of nanobiotechnology, 14, 14-14 (2016-03-05)
DNA microarrays are a core element of modern genomics research and medical diagnostics, allowing the simple and simultaneous determination of the relative abundances of hundreds of thousands to millions of genomic DNA or RNA sequences in a sample. Photolithographic in
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