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Merck
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主要文件

HPA016939

Sigma-Aldrich

Anti-SARS antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

别名:

Anti-SerRS, Anti-Serine-tRNA ligase, Anti-Seryl-tRNA synthetase, cytoplasmic, Anti-Seryl-tRNA(Ser/Sec) synthetase

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
人類蛋白質圖譜編號:
NACRES:
NA.41

价格与库存信息目前不能提供

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

產品線

Prestige Antibodies® Powered by Atlas Antibodies

形狀

buffered aqueous glycerol solution

物種活性

human

技術

immunoblotting: 0.04-0.4 μg/mL
immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:50-1:200

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此商品
756055542086348
CLED Agar suitable for microbiology, NutriSelect® Plus

55420

CLED Agar

TCBS Agar NutriSelect® Plus, suitable for microbiology

86348

TCBS Agar

form

powder

form

powder

form

powder

form

powder

suitability

selective and differential for Vibrio spp.

suitability

selective and differential for Clostridium spp.

suitability

nonselective and differential for Enterococcus spp., nonselective and differential for Escherichia coli, nonselective and differential for Klebsiella spp., nonselective and differential for Lactobacillus spp., nonselective and differential for Proteus spp., nonselective and differential for Pseudomonas spp., nonselective and differential for Salmonella spp., nonselective and differential for Staphylococcus spp., nonselective and differential for Streptococcus spp., nonselective and differential for coliforms

suitability

selective and differential for Vibrio spp.

composition

agar, 15 g/L , bromothymol blue, 0.04 g/L , cresol red, 0.04 g/L , sodium chloride, 20 g/L , cellobiose, 15 g/L , beef extract, 5 g/L , peptic digest of animal tissue, 10 g/L

composition

agar, 15 g/L , bromocresol purple, 0.04 g/L , L-cysteine hydrochloride, 1 g/L , ferric chloride 6H2O, 0.09 g/L , indoxyl-β-D-glucoside, 0.06 g/L , magnesium sulfate 7H2O, 0.1 g/L , sucrose, 5 g/L , tryptose, 30 g/L , yeast extract, 20 g/L

composition

agar, 15 g/L , beef extract, 3 g/L , bromo thymol blue, 0.02 g/L , casein enzymic hydrolysate, 4 g/L , L-cystine, 0.128 g/L , lactose, 10 g/L , peptic digest of animal tissue, 4 g/L

composition

agar, 14 g/L , bromothymol blue, 0.04 g/L , ferric citrate, 1 g/L , mixed peptone, 10 g/L , ox-bile, 5 g/L , sodium chloride, 10 g/L , sodium cholate, 3 g/L , sodium citrate, 10 g/L , sodium thiosulfate, 10 g/L , sucrose, 20 g/L , yeast extract, 5 g/L

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

application(s)

food and beverages, microbiology

application(s)

environmental
food and beverages
water monitoring, microbiology

application(s)

clinical testing
environmental
food and beverages, microbiology

application(s)

environmental
food and beverages, microbiology

一般說明

SARS (seryl-tRNA synthetase) is a novel member of the aminoacyl-tRNA synthetase family and class II tRNA synthetases. It is composed of catalytic domain with a seven-stranded anti-parallel β-sheet and three conserved sequence motifs.

免疫原

Seryl-tRNA synthetase, cytoplasmic recombinant protein epitope signature tag (PrEST)

應用

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.

生化/生理作用

SARS (seryl-tRNA synthetase) is involved in the translation and regulation of vascular development. It performs an important role in protein synthesis by catalyzing aminoacylation reaction. Mutation in SARS causes a rare mitochondrial disease, HUPRA syndrome that is coupled with hyperuricemia, pulmonary hypertension and renal failure.

特點和優勢

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

聯結

Corresponding Antigen APREST70299

外觀

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

法律資訊

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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    其他客户在看

    Henry Rivera et al.
    BMC nephrology, 14, 195-195 (2013-09-17)
    HUPRA syndrome is a rare mitochondrial disease characterized by hyperuricemia, pulmonary hypertension, renal failure in infancy and alkalosis. This syndrome was previously described in three patients with a homozygous mutation c.1169A > G (p.D390G) in SARS2, encoding the mitochondrial seryl-tRNA
    Xiaoling Xu et al.
    Structure (London, England : 1993), 21(11), 2078-2086 (2013-10-08)
    Seryl-tRNA synthetase (SerRS), an essential enzyme for translation, also regulates vascular development. This "gain-of-function" has been linked to the UNE-S domain added to vertebrate SerRS during evolution. However, the significance of two insertions also specific to higher eukaryotic SerRS remains

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