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應用
肝素黄杆菌肝素酶III已用于裂解特定GAG。已用于研究其对与抗aFGF(酸性成纤维细胞生长因子)抗体反应的蛋白质的电泳迁移率的影响。
生化/生理作用
肝素酶III可防止体内新血管的形成。它在HNY-I和HNY、6X-G2连接处特异性降解硫酸肝素。与其他肝素酶不同,肝素酶III不含氨基酸半胱氨酸。它含有13个组氨酸残基,这是其催化作用的原因。该酶对肝素或低分子量肝素没有活性。
肝素降解裂解酶,识别硫酸肝素蛋白聚糖为其主要底物。
單位定義
在25 °C、pH 7.5条件下,一个单位每小时可形成0.1 μM不饱和糖醛酸。一个国际单位(I.U.)相当于大约600个Sigma单位。包装规格基于Sigma单位。
其他說明
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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商品
Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
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