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Merck
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文件

H3661

Sigma-Aldrich

4′-羟基双氯芬酸

≥98% (HPLC)

别名:

2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸, 4′-羟基双氯灭痛

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About This Item

经验公式（希尔记法）:
C14H11Cl2NO3
CAS号:
64118-84-9
分子量:
312.15
Beilstein:
4198042
MDL號碼:
MFCD01671980
分類程式碼代碼:
12161501
PubChem物質ID:
24895589
NACRES:
NA.47

品質等級

200

化驗

≥98% (HPLC)

包裝

vial of 5 mg

儲存溫度

−20°C

SMILES 字串

OC(=O)Cc1ccccc1Nc2c(Cl)cc(O)cc2Cl

InChI

1S/C14H11Cl2NO3/c15-10-6-9(18)7-11(16)14(10)17-12-4-2-1-3-8(12)5-13(19)20/h1-4,6-7,17-18H,5H2,(H,19,20)

InChI 密鑰

KGVXVPRLBMWZLG-UHFFFAOYSA-N

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一般說明

4′-羟基双氯芬酸是一种重要的醋氯芬酸代谢物，主要存在于大鼠中。它是尿液中的重要氧化代谢物。
双氯芬酸的 CYP2C9 代谢物。

應用

4′-羟基双氯芬酸已被用于考察龙胆苦甙 (GE) 对人细胞色素P450酶的体外作用。它还被用作酶标记物，用于研究其在不同体外肝脏模型中的代谢活性。

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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