F5178

Flavin-Containing Monooxygenase-5, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

• 别名: FMO-5
• EC 号: 1.14.13.8 (BRENDA, IUBMB)
• 分類程式碼代碼: 12352204
• NACRES: NA.54

属性

• 重組細胞: expressed in baculovirus infected insect cells
• 品質等級: 200
• 形狀: buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
• 比活性: ≥700 units/mg protein
• 分子量: 55-60 kDa
• 包裝: vial of 2.5 mg
• UniProt登錄號: P49326
• 運輸包裝: dry ice
• 儲存溫度: −70°C
• 基因資訊: human ... FMO5(2330)

说明

應用

FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

生化／生理作用

FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

單位定義

methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.

外觀

Solution in 100 mM potassium phosphate buffer, pH 7.4.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)