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质量水平
方案
≥98% (HPLC)
表单
powder
旋光性
[α]27/D −7.2°, c = 0.3 in methanol(lit.)
储存条件
desiccated
颜色
off-white
溶解性
H2O: soluble >10 mg/mL
ethanol: soluble 2.6 mg/mL
0.1 M HCl: soluble 7 mg/mL
SMILES字符串
Cl.CCN1CCC[C@H]1CNC(=O)c2c(O)c(CC)cc(Cl)c2OC
InChI
1S/C17H25ClN2O3.ClH/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2;/h9,12,21H,4-8,10H2,1-3H3,(H,19,22);1H/t12-;/m0./s1
InChI key
HFJFXXDHVWLIKX-YDALLXLXSA-N
基因信息
human ... DRD2(1813)
应用
S-(-)-盐酸依替必利已用于星形胶质细胞-神经元共培养 和官能性磁共振成像 (fMRI) 实验。
生化/生理作用
强效和选择性 D2 多巴胺受体拮抗剂。依替必利对 DAD2 受体的特异性高于匹莫齐特或氟哌啶醇。编码D2多巴胺受体(DRD2)的基因与包括帕金森病在内的多种疾病、精神分裂症和酒精中毒易感性有关。
制备说明
溶液可在 4° C下储存数天
法律信息
经 Astra AB 许可生产和销售。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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