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Merck

E0251

Sigma-Aldrich

Estrone 3-sulfate sodium salt

contains ~35% Tris as stabilizer

别名:

1,3,5(10)-Estratrien-17-one 3-sulfate

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About This Item

线性分子式:
C18H21O5SNa
CAS号:
分子量:
372.41
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77

生物源

synthetic (organic)

品質等級

無菌

non-sterile

化驗

≥98% (TLC)

形狀

powder

包含

~35% Tris as stabilizer

技術

inhibition assay: suitable

溶解度

methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

[Na].[H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24

InChI

1S/C18H22O5S.Na.H/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;;/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);;/t14-,15-,16+,18+;;/m1../s1

InChI 密鑰

GQZNDBBLTDOIBE-DLEHHZMWSA-N

特點和優勢

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

包裝

Package size based on steroid content

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Carc. 2 - Lact. - Repr. 1A

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Takashi Nozawa et al.
Pharmaceutical research, 22(10), 1634-1641 (2005-09-24)
The aim of the study is to suppress the progress of estrogen-dependent breast cancer by inhibiting the membrane transporter, which mediates the internalization of estrone-3-sulfate as estrogen precursor in the cancer cells. The uptake of estrone-3-sulfate by estrogen-dependent breast cancer
E S M Silva et al.
Theriogenology, 86(7), 1749-1756 (2016-08-09)
The present study evaluated the influence of different regimens of estradiol benzoate (EB) treatments followed by a single dose of long-acting progesterone (LA P4) on plasma estrogen and P4 concentrations in noncyclic mares prepared as embryo recipients. Twenty-one anestrous mares
Christopher A Pearl et al.
Domestic animal endocrinology, 33(4), 451-459 (2006-10-13)
The steroid hormone regulation of the epididymis in a high estrogen producing animal like the boar is not currently understood. To test the hypothesis that the boar epididymis is an estrogen and androgen responsive tissue, the presence of estrogen and
Elizabeth J Folkerd et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 30(24), 2977-2980 (2012-07-18)
To investigate whether suppression of plasma estradiol and estrone sulfate levels by the aromatase inhibitors (AIs) anastrozole and letrozole is related to body mass index (BMI) in postmenopausal women with early estrogen receptor (ER) -positive breast cancer. Recent studies have
Yang Xie et al.
Endocrinology, 161(1) (2019-12-15)
Hemorrhagic shock (HS) is a potential life-threatening condition that may lead to injury to multiple organs, including the lung. The estrogen sulfotransferase (EST, or SULT1E1) is a conjugating enzyme that sulfonates and deactivates estrogens. In this report, we showed that

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