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Merck

D7159

Sigma-Aldrich

2′,3′-二脱氧胞苷 5′-三磷酸 钠盐

≥90% (HPLC)

别名:

ddCTP

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About This Item

经验公式(希尔记法):
C9H16N3O12P3
分子量:
451.16
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:

生物源

synthetic (organic)

化驗

≥90% (HPLC)

形狀

powder

溶解度

water: 1 mg/mL, clear, colorless

儲存溫度

−20°C

SMILES 字串

[Na+].NC1=NC(=O)N(C=C1)[C@H]2CC[C@@H](COP([O-])(=O)OP(O)(=O)OP(O)(O)=O)O2

InChI

1S/C9H16N3O12P3.Na/c10-7-3-4-12(9(13)11-7)8-2-1-6(22-8)5-21-26(17,18)24-27(19,20)23-25(14,15)16;/h3-4,6,8H,1-2,5H2,(H,17,18)(H,19,20)(H2,10,11,13)(H2,14,15,16);/q;+1/p-1/t6-,8+;/m0./s1

InChI 密鑰

LOOMQRBEBYCFPP-QDOHZIMISA-M

應用

通过X射线晶体学研究了ddCTP与DNA聚合酶β的复合物,对HIV逆转录酶的抑制活性有影响。

生化/生理作用

DNA 聚合酶 I 催化的链延伸抑制剂。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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