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Merck
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文件

D2155

Sigma-Aldrich

N-Dansyl-D-Ala-Gly-p-nitro-Phe-Gly

≥95% (HPLC)

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About This Item

经验公式（希尔记法）:
C28H32N6O9S
CAS号:
83960-27-4
分子量:
628.65
MDL號碼:
MFCD00133590
分類程式碼代碼:
12352204
PubChem物質ID:
24893643
NACRES:
NA.32

化驗

≥95% (HPLC)

形狀

powder

溶解度

methanol: 50 mg

儲存溫度

−20°C

SMILES 字串

CC(NS(=O)(=O)c1cccc2c(cccc12)N(C)C)C(=O)NCC(=O)NC(Cc3ccc(cc3)N(=O)=O)C(=O)NCC(O)=O

InChI

1S/C28H32N6O9S/c1-17(32-44(42,43)24-9-5-6-20-21(24)7-4-8-23(20)33(2)3)27(38)29-15-25(35)31-22(28(39)30-16-26(36)37)14-18-10-12-19(13-11-18)34(40)41/h4-13,17,22,32H,14-16H2,1-3H3,(H,29,38)(H,30,39)(H,31,35)(H,36,37)

InChI 密鑰

MIHGGGACSSHXPY-UHFFFAOYSA-N

基底

Selective fluorogenic substrate for enkephalinase.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Hitoshi Nakagawa et al.
Hypertension (Dallas, Tex. : 1979), 77(6), 1931-1939 (2021-04-13)
[Figure: see text].
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There is a paucity of data about the mechanisms by which sacubitril/valsartan (also known as LCZ696) improves outcomes in patients with heart failure. Specifically, the effects of sacubitril/valsartan on vascular function and NO bioavailability have not been investigated. We hypothesized
D Florentin et al.
Analytical biochemistry, 141(1), 62-69 (1984-08-15)
A fluorogenic peptide, dansyl-D-Ala-Gly-Phe(pNO2)-Gly (DAGNPG), was synthesized as a selective substrate for the neutral metalloendopeptidase (EC 3.4.24.11) involved in enkephalin metabolism. This enzyme, designated "enkephalinase," cleaves the Gly-Phe(pNO2) peptide bond of DAGNPG (V = 0.65 mumol/mg protein/min and Km =

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