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Merck

C9504

Sigma-Aldrich

Coenzyme Q6

别名:

2,3-Dimethoxy-5-methyl-6-(farnesylfarnesyl)-1,4-benzoquinone, Ubiquinone-30

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About This Item

经验公式(希尔记法):
C39H58O4
CAS号:
分子量:
590.88
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:

生物源

Saccharomyces cerevisiae

儲存溫度

−20°C

SMILES 字串

COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(\C)C)=C(C)C1=O

包裝

Sealed ampule.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves


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Mohammad Ozeir et al.
Chemistry & biology, 18(9), 1134-1142 (2011-09-29)
Coenzyme Q (Q), an essential component of eukaryotic cells, is synthesized by several enzymes from the precursor 4-hydroxybenzoic acid. Mutations in six of the Q biosynthesis genes cause diseases that can sometimes be ameliorated by oral Q supplementation. We establish here
Mario H Barros et al.
The Journal of biological chemistry, 280(52), 42627-42635 (2005-10-19)
Deletion of the Saccharomyces cerevisiae gene YOL008W, here referred to as COQ10, elicits a respiratory defect as a result of the inability of the mutant to oxidize NADH and succinate. Both activities are restored by exogenous coenzyme Q2. Respiration is
Beth Marbois et al.
The Journal of biological chemistry, 280(21), 20231-20238 (2005-03-29)
Coenzyme Q (Q) is a redox active lipid essential for aerobic respiration in eukaryotes. In Saccharomyces cerevisiae at least eight mitochondrial polypeptides, designated Coq1-Coq8, are required for Q biosynthesis. Here we present physical evidence for a coenzyme Q-biosynthetic polypeptide complex
Sergio Padilla-López et al.
Biochimica et biophysica acta, 1788(6), 1238-1248 (2009-04-07)
Coenzyme Q is an isoprenylated benzoquinone lipid that functions in respiratory electron transport and as a lipid antioxidant. Dietary supplementation with Q is increasingly used as a therapeutic for treatment of mitochondrial and neurodegenerative diseases, yet little is known regarding
Alejandro Martín-Montalvo et al.
The Biochemical journal, 440(1), 107-114 (2011-08-05)
CoQ(6) (coenzyme Q(6)) biosynthesis in yeast is a well-regulated process that requires the final conversion of the late intermediate DMQ(6) (demethoxy-CoQ(6)) into CoQ(6) in order to support respiratory metabolism in yeast. The gene CAT5/COQ7 encodes the Cat5/Coq7 protein that catalyses

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