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形狀
powder
技術
activity assay: suitable
基質
polystyrene/divinylbenzene
pH值
4—6
容量
~1.0 meq/g(dry)
相关类别
應用
消胆胺树脂可用于：
- 作为膳食补充剂，研究小鼠胆汁酸池大小和粪便胆汁酸排出量
- 改变胆汁酸(BA)水平，研究其对野生型(WT)、成纤维生长因子15(Fgf15)−/−和Fgf15转基因(TG)小鼠肝纤维化发展的影响
- 参与体外消化过程，研究其结合胆汁酸(BA)的能力
消胆胺树脂用于蛋白质层析、离子交换层析和阴离子交换介质。考来烯胺已被用于研究缓解胆囊切除术后腹泻、管理顽固性胆汁淤积性瘙痒和肥胖。
生化／生理作用
消胆胺是一种阳离子交换树脂。这种树脂可作为胆汁酸螯合剂，所含氯离子与小肠腔胆汁酸交换后，螯合的胆汁酸从粪便排出，使血清胆汁酸水平下降。消胆胺也用于治疗原发性高胆固醇血症。这种树脂可使低密度脂(LDL)胆固醇剂量依赖性减少。降低冠心病风险。
其他說明
交联聚苯乙烯上的季铵盐官能团
法律資訊
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Ju-Ling Liu et al.
PLoS genetics, 8(3), e1002553-e1002553 (2012-03-23)
Mammalian bile acids (BAs) are oxidized metabolites of cholesterol whose amphiphilic properties serve in lipid and cholesterol uptake. BAs also act as hormone-like substances that regulate metabolism. The Caenorhabditis elegans clk-1 mutants sustain elevated mitochondrial oxidative stress and display a
Noémie Péan et al.
Hepatology (Baltimore, Md.), 58(4), 1451-1460 (2013-05-21)
Many regulatory pathways are involved in liver regeneration after partial hepatectomy (PH) to initiate growth, protect liver cells, and sustain functions of the remnant liver. Bile acids (BAs), whose levels rise in the blood early after PH, stimulate both hepatocyte
A R Bolier et al.
Acta gastro-enterologica Belgica, 75(4), 399-404 (2013-02-14)
Pruritus can be the dominant symptom of cholestatic liver disease but is difficult to treat since unraveling its pathophysiology is a great challenge. Serum autotaxin activity correlates with pruritus intensity, but its causal relationship, expression pattern and exact mode of
Robert W Crawford et al.
PLoS pathogens, 8(9), e1002918-e1002918 (2012-10-03)
Intestinal inflammation changes the luminal habitat for microbes through mechanisms that have not been fully resolved. We noticed that the FepE regulator of very long O-antigen chain assembly in the enteric pathogen Salmonella enterica serotype Typhimurium (S. Typhimurium) conferred a
Guillermo Rodríguez-Gutiérrez et al.
Journal of agricultural and food chemistry, 62(36), 8973-8981 (2014-08-21)
A process based on a steam explosion pretreatment and alkali solution post-treatment was applied to fractionate olive stones (whole and fragmented, without seeds) and olive cake into their main constitutive polymers of cellulose (C), hemicelluloses (H), and lignin (L) under
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