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生物源
synthetic (organic)
化驗
≥99% (TLC)
形狀
powder
mp
>300 °C (lit.)
溶解度
1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
儲存溫度
room temp
SMILES 字串
O=C1NC=Nc2[nH]ncc12
InChI
1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
InChI 密鑰
OFCNXPDARWKPPY-UHFFFAOYSA-N
基因資訊
human ... XDH(7498)
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應用
别嘌呤醇已用于：
- 降低尿酸浓度，研究其对小鼠肾损伤和炎症的疗效
- 作为黄嘌呤氧化酶抑制剂，检测杀白细胞素(PVL)中性粒细胞胞外诱捕网(NETosis)对人多形核细胞(hPMN)不同酶、通道或细胞器的依赖性
- 作为参考标准品，体外研究橄榄叶组分对黄嘌呤氧化酶的抑制作用
别嘌呤醇适合：
- 静脉注射小鼠抑制黄嘌呤氧化酶
- 用作黄嘌呤氧化酶抑制剂
- 用作黄嘌呤氧化酶抑制试验的阳性对照
- 制备威斯康星大学保存液，用于在猪胰岛纯化中保持渗透压稳定，增强胰岛和胰腺泡片段的密度差异
生化／生理作用
别嘌呤醇是一种嘌呤类似物，可抑制某些参与嘌呤代谢的酶。减少体内的尿酸合成。别嘌呤醇可抑制黄嘌呤氧化酶，对动脉粥样硬化、急性肺损伤和充血性心力衰竭具有抗炎作用。
黄嘌呤氧化酶和初始嘧啶生物合成的抑制剂。治疗高尿酸血症和痛风的经典药物。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral - Skin Sens. 1
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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