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Merck

A5626

Sigma-Aldrich

氯化乙酰硫代胆碱

≥99% (TLC), powder

别名:

(2-Mercaptoethyl)trimethylammonium chloride acetate

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About This Item

线性分子式:
CH3COSCH2CH2N(CH3)3Cl
CAS号:
分子量:
197.73
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.83

化驗

≥99% (TLC)

形狀

powder

溶解度

water: 100 mg/mL, clear to slightly hazy, colorless

儲存溫度

−20°C

SMILES 字串

[Cl-].CC(=O)SCC[N+](C)(C)C

InChI

1S/C7H16NOS.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI 密鑰

GZYVLKKMMDFCKR-UHFFFAOYSA-M

基因資訊

human ... ACHE(43)

應用

氯化乙酰胆碱用于确定精液外泌体(SE)中乙酰胆碱酯酶的活性。也可用作乙酰胆碱酯酶的底物,对其动力学参数进行微量量热研究。

生化/生理作用

乙酰胆碱酯酶(AChE)酶在神经传递过程中起着重要的生理作用。
乙酰胆碱酯酶底物和烟碱型乙酰胆碱受体激动剂。

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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The increasing number of Alzheimer's disease (AD) cases requires the development of new improved drug candidates, possessing the ability of more efficient treatment as well as less unwanted side effects. Cholinesterase enzymes are highly associated with the development of AD
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Non-selective inhibitors of cholinesterases (ChEs) are clinically used for treatment of myasthenia gravis (MG). While being generally safe, they cause numerous adverse effects including induction of hyperactivity of urinary bladder and intestines affecting quality of patients life. In this study
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Organic & biomolecular chemistry, 14(47), 11220-11229 (2016-11-15)
The marine secondary metabolite stryphnusin (1) was isolated from the boreal sponge Stryphnus fortis, collected off the Norwegian coast. Given its resemblance to other natural acetylcholinesterase antagonists, it was evaluated against electric eel acetylcholinesterase and displayed inhibitory activity. A library

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