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方案
≥98% (HPLC)
表单
solid
颜色
white to faint yellow
溶解性
DMSO: 1 mg/mL
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
cell wall synthesis | interferes
储存温度
−20°C
InChI
1S/C13H13N5O5S2.Na/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18;/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22);/q;+1/p-1/b17-7-;/t8-,11-;/m1./s1
InChI key
ADLFUPFRVXCDMO-LIGXYSTNSA-M
生化/生理作用
Ceftizoxime is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.
包装
50mg
其他说明
Keep container tightly closed in a dry and well-ventilated place.
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Soraya Maria Zandim Maciel Dias Ferreira et al.
Bioorganic & medicinal chemistry letters, 22(14), 4605-4608 (2012-06-26)
Osteomyelitis is an infectious disease located in the bone or bone marrow. Long-circulating and pH-sensitive liposomes containing a technetium-99m-labeled antibiotic, ceftizoxime, (SpHL-(99m)Tc-CF) were developed to identify osteomyelitis foci. Biodistribution studies and scintigraphic images of bone infection or non infection-bearing rats
Bashier Osman et al.
BMC research notes, 6, 57-57 (2013-02-12)
A prophylactic antibiotic is recommended to reduce infection-related complication following cesarean delivery. There is a current debate on the time of prophylactic antibiotic in cesarean delivery. An opened randomized, controlled clinical trial was conducted at Soba hospital, Sudan to investigate
M Jayahar Bharathi et al.
Ophthalmic research, 47(1), 52-56 (2011-07-02)
To evaluate resistances mediated by extended-spectrum β-lactamases (ESBLs) and AmpC β-lactamases among Gram-negative bacteria recovered from ocular infections. As per the Clinical Laboratory Standards Institute M100-S-16 document, a total of 135 Gram-negative bacilli were recovered from ocular specimens and were
Thomas M Hooton et al.
JAMA, 307(6), 583-589 (2012-02-10)
Although fluoroquinolones remain the most reliable urinary antimicrobial, resistance rates have increased and effective fluoroquinolone-sparing antimicrobials are needed. To determine whether cefpodoxime is noninferior to ciprofloxacin for treatment of acute cystitis. Randomized, double-blind trial of 300 women aged 18 to
Peymaneh Alizadeh Taheri et al.
Acta medica Iranica, 49(8), 499-503 (2011-10-20)
Neonatal sepsis, a life-threatening condition, presents with non-specific clinical manifestations and needs immediate empirical antimicrobial therapy. Choosing an appropriate antibiotic regimen covering the most probable pathogens is an important issue. In this study we compared the effectiveness of ceftizoxime and
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