所有图片(1)
About This Item
经验公式（希尔记法）:
C20H30N4O11
CAS号:
分子量:
502.47
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.32
推荐产品
生物源
synthetic
品質等級
化驗
≥95%
形狀
powder
顏色
white
溶解度
H2O: 1 mg/mL
儲存溫度
−20°C
SMILES 字串
[H]C(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(C)=O)C(C)C
InChI
1S/C20H30N4O11/c1-9(2)17(20(35)22-11(8-25)6-15(29)30)24-18(33)12(4-5-14(27)28)23-19(34)13(7-16(31)32)21-10(3)26/h8-9,11-13,17H,4-7H2,1-3H3,(H,21,26)(H,22,35)(H,23,34)(H,24,33)(H,27,28)(H,29,30)(H,31,32)
InChI 密鑰
UMBVAPCONCILTL-UHFFFAOYSA-N
基因資訊
human ... CASP1(834) , CASP3(836) , CASP7(840) , CASP8(841)
Amino Acid Sequence
NAc-Asp-Glu-Val-Asp-al
一般說明
N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) 是一种具有N端乙酰化和C端醛共轭的四肽。
應用
N-Acetyl-Asp-Glu-Val-Asp-al已在肌肉样品、平滑肌细胞和Jurkat T细胞中被用作半胱氨酸蛋白酶抑制剂。
生化／生理作用
N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) 可通过其半胱氨酸蛋白酶抑制剂的功能性有助于顿抑心肌的恢复。
IL-1β的可逆性抑制剂；转化酶（ICE）；通过凋亡蛋白（caspase 3）抑制聚（ADP-核糖）聚合酶的切割。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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