所有图片(1)
About This Item
经验公式(希尔记法):
C21H26O3
CAS号:
分子量:
326.43
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.25
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品質等級
化驗
≥98.0% (HPLC)
形狀
powder
SMILES 字串
COc1cc(C)c(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)c(C)c1C
InChI
1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+
InChI 密鑰
IHUNBGSDBOWDMA-AQFIFDHZSA-N
基因資訊
human ... RARA(5914) , RARB(5915) , RARG(5916) , RXRA(6256) , RXRB(6257) , RXRG(6258)
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應用
阿维 A 是一种可与核受体结合并调节基因表达的类视黄醇,是通过 CD95 信号通路的 α-分泌酶 ADAM10 基因表达和凋亡诱导剂的有效激活剂。 阿维 A 是一种用于治疗严重银屑病的全身性维甲酸类药物。
生化/生理作用
合成维甲酸,是依曲甲酸酯的代谢物。 优先与细胞视黄酸结合蛋白(CRABP) 结合。
訊號詞
Danger
危險分類
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
儲存類別代碼
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
其他客户在看
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Late-onset Alzheimer's disease is often connected with nutritional misbalance, such as enhanced cholesterol intake, deficiency in polyunsaturated fatty acids, or hypovitaminosis. The alpha-secretase ADAM10 has been found to be regulated by retinoic acid, the bioreactive metabolite of vitamin A. Here
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