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生物源
rabbit
品質等級
100
500
共軛
unconjugated
抗體表格
Ig fraction of antiserum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (403A-74)
vial of 0.5 mL concentrate (403A-75)
bottle of 1.0 mL predilute (403A-77)
vial of 1.0 mL concentrate (403A-76)
bottle of 7.0 mL predilute (403A-78)
製造商／商標名
Cell Marque™
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
cytoplasmic, membranous
基因資訊
human ... CR2(1380)
一般說明
Complement component C3 is an integral part of the classical, lectin, and alternative complement pathways, and its cleavage products are involved in immune responses such as opsonization and cell lysis. C3d is a fragment of C3 that normally binds to pathogen surfaces to promote B-cell activation. However, deposition of C3d has also been observed in peritubular capillaries of transplanted kidneys undergoing acute allograft rejection.
品質
 IVD |  IVD |  IVD |  RUO |
聯結
C3d Positive Control Slides, Product No. 403S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律資訊
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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Dirk R J Kuypers et al.
Transplantation, 76(1), 102-108 (2003-07-17)
C4d deposition in peritubular capillaries (PTCs) is a sign of humoral renal allograft rejection and an independent predictor of graft survival. Few investigators have focused on the meaning of capillary C3 deposition in rejecting grafts. Because C3 production can result
Alice Bickerstaff et al.
The American journal of pathology, 173(2), 347-357 (2008-06-28)
Acute humoral rejection (AHR), which occurs in up to 8% of kidney transplant recipients, is a significant cause of renal allograft dysfunction and loss. More efficacious treatment modalities are needed to eliminate or curtail alloantibody production and its deleterious effects
Katrin Pfaltz et al.
Journal of cutaneous pathology, 37(6), 654-658 (2009-10-30)
Direct immunofluorescence (DIF) testing is an important procedure in the diagnosis of autoimmune bullous dermatoses. We investigated the expression of C3d in formalin-fixed, paraffin-embedded tissue of autoimmune bullous dermatoses. The immunohistochemical expression of C3d in bullous pemphigoid (BP) (n =
G Eggertsen et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 109(12), 825-834 (2002-02-16)
Among patients with early severe impairment of renal allograft function we have previously identified a group displaying isolated deposition of complement factor C3 in glomeruli. Here we studied the pattern of complement deposition more extensively in allograft biopsies from five
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