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產品線
BioReagent
化驗
≥97.5% (HPLC)
形狀
powder
mp
≥350 °C (lit.)
溶解度
DMSO: soluble
螢光
λex 377 nm; λem 437 nm in 0.1 M Tris pH 8.0
適合性
suitable for fluorescence
SMILES 字串
Oc1ccc-2c(OC(=O)c3c-2oc4cc(O)ccc34)c1
InChI
1S/C15H8O5/c16-7-1-3-9-11(5-7)19-14-10-4-2-8(17)6-12(10)20-15(18)13(9)14/h1-6,16-17H
InChI 密鑰
ZZIALNLLNHEQPJ-UHFFFAOYSA-N
基因資訊
human ... ESR1(2099) , ESR2(2100)
mouse ... Esr1(13982)
rat ... Ar(24208)
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生化／生理作用
香豆酚通过雌激素受体-α的介导而对大脑和垂体具有抗雌激素作用。
訊號詞
Warning
危險分類
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Man-Hai Liu et al.
Neurological research, 33(6), 663-672 (2011-06-29)
Estrogen replacement therapy can decrease the risk of developing Alzheimer's disease. Phytoestrogens have been proposed as potential alternatives to estrogen replacement therapy. The purpose of this study was to evaluate the in vitro protective effects of coumestrol on mice astrocytes.
Corinne C Hoerger et al.
Journal of agricultural and food chemistry, 59(3), 847-856 (2011-01-06)
We developed and validated three different sample preparation and extraction methods followed by HPLC-MS/MS (negative electrospray ionization) analysis for the quantification of estrogenic isoflavones (formononetin, daidzein, equol, biochanin A, and genistein) and coumestrol in red clover, soil, and manure. Plant
Elisa V Bandera et al.
BMC women's health, 11, 40-40 (2011-09-29)
While there is extensive literature evaluating the impact of phytoestrogen consumption on breast cancer risk, its role on ovarian cancer has received little attention. We conducted a population-based case-control study to evaluate phytoestrogen intake from foods and supplements and epithelial
Sarah J Lowry et al.
Nutrition and cancer, 64(6), 783-789 (2012-08-07)
Some forms of estrogen are associated with breast cancer risk as well as with mammographic density (MD), a strong marker of breast cancer risk. Whether phytoestrogen intake affects breast density, however, remains unclear. We evaluated the association between serum levels
Gail A Greendale et al.
Menopause (New York, N.Y.), 19(8), 894-903 (2012-03-15)
Phytoestrogens, which consist mainly of isoflavones, lignans, and coumestans have estrogenic and anti-inflammatory properties. Previous research suggests that higher dietary or supplemental intakes of isoflavones and lignans are related to better cognitive performance in middle-aged and older women. We conducted
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