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213942

Sigma-Aldrich

3-甲基胆蒽

98%

别名:

20-Methylcholanthrene, Methylcholanthrene

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About This Item

经验公式（希尔记法）:
C21H16
CAS号:
56-49-5
分子量:
268.35
Beilstein:
1913890
EC號碼:
200-276-4
MDL號碼:
MFCD00003704
分類程式碼代碼:
12352005
PubChem物質ID:
57647926
NACRES:
NA.25

品質等級

200

化驗

98%

形狀

solid

bp

280 °C/80 mmHg (lit.)

mp

178-180 °C (lit.)

SMILES 字串

Cc1ccc2cc3c(ccc4ccccc34)c5CCc1c25

InChI

1S/C21H16/c1-13-6-7-15-12-20-17-5-3-2-4-14(17)8-9-18(20)19-11-10-16(13)21(15)19/h2-9,12H,10-11H2,1H3

InChI 密鑰

PPQNQXQZIWHJRB-UHFFFAOYSA-N

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應用

3-甲基胆蒽用于通过 Bhas 42细胞转化测定评估其肿瘤引发活性。也用来诱导细胞色素 P450 的活性。

生化／生理作用

3-甲基胆蒽是致癌物质，用于诱导培养细胞转化。也可用于诱发实验动物发生纤维肉瘤和皮肤癌。3-甲基胆蒽是芳香烃受体的强效激动剂。

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H350,H413

危險分類

Aquatic Chronic 4 - Carc. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCW4323
MKCM7171
MKCG2810
MKBS1548V
MKBQ8665V

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Natural killer (NK) T cells initiate potent antitumor responses when stimulated by exogenous factors such as interleukin (IL)-12 or alpha-galactosylceramide (alpha-GalCer), however, it is not clear whether this reflects a physiological role for these cells in tumor immunity. Through adoptive
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The two estrogen receptor isoforms ERα and ERβ mediate biological effects of estrogens, but are also targets for endocrine disruptive chemicals (EDCs), compounds that interfere with hormonal signaling. 3-Methylcholanthrene (3-MC) and dioxin (TCDD) are EDCs and prototypical aryl hydrocarbon receptor
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