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生物源
rabbit
品質等級
100
500
共軛
unconjugated
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
SP149, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (118R-14)
vial of 0.5 mL concentrate (118R-15)
bottle of 1.0 mL predilute (118R-17)
vial of 1.0 mL concentrate (118R-16)
bottle of 7.0 mL predilute (118R-18)
製造商／商標名
Cell Marque™
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
同型
IgG
控制
bone marrow, lymph node, plasma cell myeloma
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
cytoplasmic
基因資訊
human ... CD38(952)
一般說明
CD38 molecule is a 46-kDa type-II transmembrane glycoprotein with a short N-terminalcytoplasmic tail (20 amino acids) and a long extracellular domain (256 amino acids). Itis present on many hematopoietic cells, especially plasma cells, and in some solid tumortissues. CD38 is one of the early expressed markers of mature naive B-cell activation and it isuseful in identifying functional mature B-lymphocyte subsets.
品質
 IVD |  IVD |  IVD |  RUO |
聯結
CD38 Positive Control Slides, Product No. 118S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律資訊
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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Flavius Martin et al.
Nature reviews. Immunology, 2(5), 323-335 (2002-05-30)
Recent advances in genomics and proteomics, combined with the facilitated generation and analysis of transgenic and gene-knockout animals, have revealed new complexities in classical biological systems, including the B-cell compartment. Studies on an 'old', but poorly characterized, B-cell subset--the naive
Leoncini, L et al. Burkitt lymphoma. In Swerdlow SH, et al. eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. IARC, WHO Press, Lyon, France, 2008; 262-264.
Leoncini, L
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 262-264 (2008)
Kikkeri N Naresh et al.
British journal of haematology, 154(6), 770-776 (2011-07-02)
Distinguishing Burkitt lymphoma (BL) from B cell lymphoma, unclassifiable with features intermediate between diffuse large B-cell lymphoma (DLBCL) and BL (DLBCL/BL), and DLBCL is challenging. We propose an immunohistochemistry and fluorescent in situ hybridization (FISH) based scoring system that is
Fabio Malavasi et al.
Physiological reviews, 88(3), 841-886 (2008-07-16)
The membrane proteins CD38 and CD157 belong to an evolutionarily conserved family of enzymes that play crucial roles in human physiology. Expressed in distinct patterns in most tissues, CD38 (and CD157) cleaves NAD(+) and NADP(+), generating cyclic ADP ribose (cADPR)
Sandeep S Dave et al.
The New England journal of medicine, 354(23), 2431-2442 (2006-06-09)
The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma is crucial because these two types of lymphoma require different treatments. We examined whether gene-expression profiling could reliably distinguish Burkitt's lymphoma from diffuse large-B-cell lymphoma. Tumor-biopsy specimens from 303 patients with
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