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Merck

Y0000572

羟乙膦酸钠 二钠

European Pharmacopoeia (EP) Reference Standard

别名:

1-Hydroxyethane-1,1-bisphosphonic acid disodium salt

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About This Item

经验公式(希尔记法):
C2H6Na2O7P2
CAS号:
分子量:
249.99
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

etidronate

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

InChI

1S/C2H8O7P2.2Na/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2

InChI 密鑰

GWBBVOVXJZATQQ-UHFFFAOYSA-L

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Etidronate disodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

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Determination of etidronate disodium tablets by ion chromatography with indirect UV detection.
Tsai E W, et al.
Journal of Pharmaceutical and Biomedical Analysis, 11(6), 513-516 (1993)
S M Krane
Annals of internal medicine, 96(5), 619-625 (1982-05-01)
Control of Paget's disease of bone has been possible through treatment with agents that decrease bone resorption; calcitonins, diphosphonates, and mithramycin. The pagetic lesion is not, however, cured. Etidronate disodium is one of the diphosphonates. The clinical improvement attained with
The role of risedronate in osteopenia in Crohn's disease.
Alice Buchan et al.
Gut, 64(1), 185-185 (2013-12-07)
Ivana Sestak et al.
The Lancet. Oncology, 15(13), 1460-1468 (2014-12-03)
Aromatase inhibitors prevent breast cancer in postmenopausal women at high risk of the disease but are associated with accelerated bone loss. We assessed effectiveness of oral risedronate for prevention of reduction in bone mineral density (BMD) after 3 years of
Jörg Schilcher et al.
Acta orthopaedica, 86(1), 100-107 (2015-01-15)
Use of bisphosphonates in women is associated with higher risk of atypical femoral fractures. The risk in terms of timing of use and type of bisphosphonate, and in men, remains unclear. We reviewed radiographs of 5,342 Swedish women and men

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