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Merck
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主要文件

T3000000

短杆菌素

European Pharmacopoeia (EP) Reference Standard

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About This Item

CAS号:
1404-88-2
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

tyrothricin

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

N21[C@@H](CCC2)C(=O)N[C@H](C(=O)N[C@@H](C(=O)[C@@H](NC(=O)[C@@H](N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](C1=O)Cc6ccccc6)CC(C)C)CCCN)C(C)C)Cc5ccc(cc5)O)CCC(=O)O)CC(=O)N)Cc4ccccc4)Cc3ccccc3

InChI

1S/C65H85N11O13/c1-38(2)32-49-60(84)74-52(36-42-20-12-7-13-21-42)65(89)76-31-15-23-53(76)63(87)73-51(34-41-18-10-6-11-19-41)61(85)70-47(33-40-16-8-5-9-17-40)57(81)48(37-54(67)78)71-59(83)46(28-29-55(79)80)68-50(35-43-24-26-44(77)27-25-43)62(86)75-56(39(3)4)64(88)69-45(22-14-30-66)58(82)72-49/h5-13,16-21,24-27,38-39,45-53,56,68,77H,14-15,22-23,28-37,66H2,1-4H3,(H2,67,78)(H,69,88)(H,70,85)(H,71,83)(H,72,82)(H,73,87)(H,74,84)(H,75,86)(H,79,80)/t45-,46-,47+,48-,49-,50-,51-,52+,53-,56-/m0/s1

InChI key

NLJVXZFCYKWXLH-DXTIXLATSA-N

相关类别

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Tyrothricin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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C Bayerl et al.
Die Pharmazie, 59(11), 864-868 (2004-12-14)
The efficacy and tolerance of an antiseptic wound powder based on the antibiotic tyrothricin was investigated in a prospective, randomized multicenter trial in patients with posttraumatic and surgical cutaneous lesions. In 5 centers, 131 male and female patients from 18-85
H H Paradies
Journal of pharmaceutical sciences, 78(3), 230-234 (1989-03-01)
Aqueous solutions of tyrocidine B, iodoacetyltyrocidine B, and diiodotyrocidine B in 40% H2O:60% ethanol (w/w) were investigated by analytical ultracentrifugation, light scattering, and small-angle X-ray scattering techniques. A reasonable hydrodynamic description of the aggregates of molecular weight 28,600 is a
M A Marahiel et al.
Journal of bacteriology, 169(5), 2215-2222 (1987-05-01)
Tyrocidine is a cyclic decapeptide antibiotic which is produced and secreted by stationary-phase cells of the sporeforming bacterium Bacillus brevis. We identified the promoter for the B. brevis structural gene (tycA) for tyrocidine synthetase I, the enzyme catalyzing the first
[Antiseptic activity of a formaldehyde-tyrothricin combination and its effect on gingival inflammation].
J P Rocca et al.
L' Information dentaire, 70(3), 149-155 (1988-01-21)
Johan Arnold Vosloo et al.
Microbiology (Reading, England), 159(Pt 10), 2200-2211 (2013-08-22)
A group of non-ribosomally produced antimicrobial peptides, the tyrocidines from the tyrothricin complex, have potential as antimicrobial agents in both medicine and industry. Previous work by our group illustrated that the more polar tyrocidines rich in Trp residues in their
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