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Merck

PHR1717

Supelco

甲基强的松龙

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

6α-甲基泼尼松龙, 11β,17α,21-三羟基-6α-甲基-1,4-孕甾二烯-3,20-二酮, 6α-甲基-11β,17α,21-三羟基-1,4-孕甾二烯-3,20-二酮, 甲基强的松龙, 甲基泼尼松龙

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About This Item

经验公式(希尔记法):
C22H30O5
CAS号:
分子量:
374.47
Beilstein:
2340300
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to BP 248
traceable to Ph. Eur. M1750000
traceable to USP 1435003

API 家族

methylprednisolone

CofA

current certificate can be downloaded

包裝

pkg of 500 mg

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-30°C

SMILES 字串

[H][C@@]12C[C@H](C)C3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO

InChI

1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1

InChI 密鑰

VHRSUDSXCMQTMA-PJHHCJLFSA-N

基因資訊

human ... NR3C1(2908)

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一般說明

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Methylprednisolone is a synthetic corticosteroid drug which is employed for the management of inflammatory diseases. It is used to relieve the inflammations caused by psoriasis, eczema, arthritis, asthma and rhinitis. It is also widely employed for the treatment of acute lung injury caused by acid aspiration.

應用

Methylprednisolone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and counterfeit cosmetic products by chromatography and electroanalytical techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAB8710 in the slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

相關產品

产品编号
说明
价格

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Repr. 1B - STOT RE 2

標靶器官

Adrenal gland,Immune system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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访问文档库

Methylprednisolone
USP42-NF37
United States Pharmacopeia/National Formulary, 44(3), 2859-2859 (2013)
Differential pulse voltammetric determination of methylprednisolone in pharmaceuticals and human biological fluids
Goyal RN, et al.
Analytica Chimica Acta, 605(1), 34-40 (2007)
LC-MS method for the simultaneous determination of six glucocorticoids in pharmaceutical formulations and counterfeit cosmetic products
Fiori J and Andrisano V
Journal of Pharmaceutical and Biomedical Analysis, 91, 185-192 (2014)
Simultaneous determination of cortisol, dexamethasone, methylprednisolone, prednisone, prednisolone, mycophenolic acid and mycophenolic acid glucuronide in human plasma utilizing liquid chromatography-tandem mass spectrometry
DiFrancesco R, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 859(1), 42-51 (2007)
Determination of methylprednisolone acetate in biological fluids at gold nanoparticles modified ITO electrode
Goyal RN, et al.
Journal of Pharmaceutical and Biomedical Analysis, 44(5), 1147-1153 (2007)

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