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Merck

PHR1216

Supelco

癸二酸二丁酯

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

癸二酸二正丁酯, 皮脂酸二丁酯

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About This Item

线性分子式:
[-(CH2)4CO2(CH2)3CH3]2
CAS号:
分子量:
314.46
Beilstein:
1798308
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to USP 1187091

API 家族

dibutyl sebacate

CofA

current certificate can be downloaded

技術

HPLC: suitable
gas chromatography (GC): suitable

折射率

n20/D 1.441 (lit.)

bp

178-179 °C/3 mmHg (lit.)

密度

0.936 g/mL at 25 °C (lit.)

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-30°C

SMILES 字串

CCCCOC(=O)CCCCCCCCC(=O)OCCCC

InChI

1S/C18H34O4/c1-3-5-15-21-17(19)13-11-9-7-8-10-12-14-18(20)22-16-6-4-2/h3-16H2,1-2H3

InChI 密鑰

PYGXAGIECVVIOZ-UHFFFAOYSA-N

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一般說明

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Dibutyl sebacate is a commonly used plasticizer, which can be synthesized by the reaction of butyl alcohol and sebacyl chloride or by the distillation of sebacic acid with butyl alcohol in the presence of concentrated hydrochloric acid in benzene solution.

應用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA9029 in the slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

366.8 °F - open cup

閃點(°C)

186 °C - open cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Burdock AG et al.
Encyclopedia of Food & Color Additives, 1 (1997)
T Quinten et al.
Drug development and industrial pharmacy, 37(2), 149-159 (2010-07-10)
It was the aim of the present study to develop sustained-release matrix tablets by means of injection molding of ethylcellulose (EC) and polyethylene oxide (PEO) mixtures and to evaluate the influence of process temperature, matrix composition, and viscosity grade of
Kangarlou Sogol et al.
International journal of pharmaceutics, 408(1-2), 1-8 (2010-11-26)
The object of this study was to investigate the influence of static and dynamic forces on mechanical properties of the biocompatible polymer ethyl cellulose. Similar polymeric films containing 40% (w/w) of the plasticizer dibutyl sebacate were subjected to tensile forces
Thomas Quinten et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 71(1), 145-154 (2008-05-31)
The aim of this study was to develop sustained-release matrix tablets by means of injection moulding and to evaluate the influence of process temperature, matrix composition (EC and HPMC concentration) and viscosity grade of ethylcellulose (EC) and hydroxypropylmethylcellulose (HPMC) on
A Wyss et al.
Biotechnology and bioengineering, 87(6), 734-742 (2004-08-27)
A novel perstraction system using liquid-core microcapsules for pesticide and herbicide removal from aqueous environments is proposed. The microcapsules contain an oil, dibutyl sebacate, surrounded by a hydrogel membrane. The extraction efficiency of the capsules was demonstrated with atrazine, methylparathion

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