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Merck
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文件

O4630

Supelco

奥芬那君 柠檬酸盐

analytical standard

别名:

β-二甲基氨基乙基-2-甲基二苯甲醚 柠檬酸盐, 邻甲苯海明 柠檬酸盐

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About This Item

经验公式（希尔记法）:
C18H23NO · C6H8O7
CAS号:
4682-36-4
分子量:
461.50
EC號碼:
225-137-5
MDL號碼:
MFCD00079197
分類程式碼代碼:
41116107
PubChem物質ID:
329818911
NACRES:
NA.24

等級

analytical standard

品質等級

200

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

OC(=O)CC(CC(O)=O)C(O)=O.CN(C)CCOC(c1ccccc1)c2ccccc2C

InChI

1S/C18H23NO.C6H8O6/c1-15-9-7-8-12-17(15)18(20-14-13-19(2)3)16-10-5-4-6-11-16;7-4(8)1-3(6(11)12)2-5(9)10/h4-12,18H,13-14H2,1-3H3;3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI 密鑰

XLSFUJUURNFSCL-UHFFFAOYSA-N

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應用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化／生理作用

毒蕈碱型受体拮抗剂；H1 组胺受体拮抗剂；肌肉松弛剂。据报道，奥芬那君还可抑制去甲肾上素转运蛋白并且阻塞 NMDA 受体离子通道。

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析证书(COA)

Lot/Batch Number
048F0510V
048F0510
048F0510

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M A Saracino et al.
Journal of pharmaceutical and biomedical analysis, 50(3), 501-506 (2009-06-16)
Orphenadrine is an antimuscarinic agent mainly used for the treatment of parkinsonism and to alleviate the neuroleptic syndrome induced by antipsychotic drugs. A new, rapid analytical method, based on liquid chromatography with diode array detection (DAD), has been developed and
Mirosław Czuczwar et al.
Pharmacological reports : PR, 61(4), 732-736 (2009-10-10)
Orphenadrine is an anticholinergic drug used in the treatment of Parkinson's disease, and is also known to exert nonspecific antagonistic activity at the phencyclidine binding site of the N-methyl-D-aspartate (NMDA) receptor. The aim of this study was to assess the
Mei-juan Xu et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 42(7), 730-734 (2007-09-22)
To study the enzyme kinetics of schizandrin metabolism in different gender in rat liver microsomes, liver microsomes were prepared from male or female rats. Schizandrin was incubated with rat liver microsomes. Schizandrin and its metabolites were isolated and identified by
[Interaction of drugs with the primary disease - when medicines exacerbate illnesses].
Anne Taegtmeyer et al.
Praxis, 101(6), 363-370 (2012-03-16)
Marianna Borsodi et al.
Orvosi hetilap, 149(39), 1847-1852 (2008-09-23)
The authors compared the potency, safety and tolerability of combined infusion containing non-steroid anti-inflammation diclofenac and central muscle relaxant orphenadrine, and those of tramadol HCl, during postoperative pain relief after low and middle category operations. The test was an open
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