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等級
analytical standard
品質等級
技術
HPLC: suitable
gas chromatography (GC): suitable
應用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
格式
neat
SMILES 字串
CC(C)C1=C(CN(C)C(C)Cc2ccccc2)N(C)N(c3ccccc3)C1=O
InChI
1S/C24H31N3O/c1-18(2)23-22(17-25(4)19(3)16-20-12-8-6-9-13-20)26(5)27(24(23)28)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3
InChI 密鑰
GNUXVOXXWGNPIV-UHFFFAOYSA-N
一般說明
Famprofazone is a pyrazole derivative and belongs to the class of non-steroidal anti-inflammatory drugs. It is widely used as an analgesic and antipyretic in medical applications.
應用
Famprofazone may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Journal of analytical toxicology, 27(7), 479-484 (2003-11-11)
There are a several drugs that lead to the production of methamphetamine and/or amphetamine in the body which are subsequently excreted in the urine. These drugs raise obvious concerns when interpreting positive amphetamine drug testing results. Famprofazone is an analgesic
International journal of legal medicine, 111(6), 305-308 (1998-11-24)
After a traffic accident a 32-year-old man was suspected of having previously taken an illegal drug. An immunochemical screening procedure revealed positive results for amphetamines in both urine and blood samples. The preliminary test was confirmed by GC/MS and both
Chirality, 9(1), 52-58 (1997-01-01)
Following administration of famprofazone to humans, the stereoselective metabolism from the drug to its known metabolites (+,-)-ephedrine, (+,-)-pseudoephedrine, (+,-)-norephedrine, (+,-)-norpseudoephedrine, (+,-)-p-hyroxyamphetamine, (+,-)-p-hydroxymethamphetamine, and (+,-)-p-hydroxynorephedrine was studied. The enantiomers of the metabolites were derivatized with alpha-methoxy-alpha -(trifluoromethyl)-phenylacetyl chloride (MPTA.Cl) as the
A rapid screening LC?MS/MS method based on conventional HPLC pumps for the analysis of low molecular weight xenobiotics: application to doping control analysis
Drug Testing and Analysis, 2(7), 311-322 (2010)
Forensic Science
Handbook of Analytical Chemistry, 6(7), 311-322 (2011)
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