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主要文件

D6001

Sigma-Aldrich

硫酸葡聚糖 钠盐 来源于明串珠菌

average mol wt >500,000 (dextran starting material), contains 0.5-2.0% phosphate buffer, pH 6-8

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352201
NACRES:
NA.21

生物源

bacterial (Leuconostoc mesenteroides)

品質等級

形狀

powder

光學活性

[α]/D 90 to 105 °, c = 6% (w/v) in water

分子量

average mol wt >500,000 (dextran starting material)

包含

0.5-2.0% phosphate buffer, pH 6-8

成份

Sulfur Content, 16.0-19.0%

顏色

white to off-white

有用的pH值範圍

6.0-8.0 (1% in water)

溶解度

H2O: 100 mg/mL

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一般說明

硫酸葡聚糖是带负电荷的硫酸化多糖, 可由葡聚糖与氯磺酸的酯化反应产生。具有抗病毒、抗凝血和佐剂特性。葡聚糖用于治疗出血、烧伤、手术伤口和创伤。可以增加血流量,阻断红细胞聚集。葡聚糖降低血栓形成和术后肺栓塞风险。作为核糖核酸酶抑制剂发挥作用。

應用

从明串珠菌属某些种(Leuconostoc spp)中提取的硫酸葡聚糖钠盐可用于:
  • 使含脂肪的血浆脱脂(67)(70)
  • 诱发啮齿类动物远端结肠发生炎症和致癌反应(68)
  • 制备3,4-乙撑二氧噻吩(EDOT)(69)

其他說明

为了全面了解我们针对客户研究提供的各种葡聚糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Julien Charest et al.
Developmental cell, 55(4), 483-499 (2020-10-02)
Combinatorial action of transcription factors (TFs) with partially overlapping expression is a widespread strategy to generate novel gene-expression patterns and, thus, cellular diversity. Known mechanisms underlying combinatorial activity require co-expression of TFs within the same cell. Here, we describe the
PEDOT doped with algal, mammalian and synthetic dopants: polymer properties, protein and cell interactions, and influence of electrical stimulation on neuronal cell differentiation
Molino PJ, et al.
Biomaterials Science, 6(5), 1250-1261 (2018)
Delipidation of plasma has minimal effects on human butyrylcholinesterase
Onder S, et al.
Frontiers in Pharmacology, 9, 117-117 (2018)
The Molecular Biology of Poliovirus (2012)
Seda Onder et al.
Frontiers in pharmacology, 8, 713-713 (2017-10-27)
Hupresin is a new affinity resin that binds butyrylcholinesterase (BChE) in human plasma and acetylcholinesterase (AChE) solubilized from red blood cells (RBC). Hupresin is available from the CHEMFORASE company. BChE in human plasma binds to Hupresin and is released with

实验方案

硫酸葡聚糖以钠盐形式供应,使其在水中可溶且稳定。硫酸葡聚糖含有大约17%的硫,相当于每个葡糖基残基大约有2.3个硫酸基团。

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

相关内容

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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