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Merck

80714

Supelco

丹参酮 I

analytical standard

别名:

丹参酮 Ⅰ, 丹参酮A, 丹参醌 I

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About This Item

经验公式(希尔记法):
C18H12O3
CAS号:
分子量:
276.29
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

方案

≥98.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

food and beverages

包装形式

neat

储存温度

2-8°C

SMILES字符串

Cc1coc2-c3ccc4c(C)cccc4c3C(=O)C(=O)c12

InChI

1S/C18H12O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h3-8H,1-2H3

InChI key

AIGAZQPHXLWMOJ-UHFFFAOYSA-N

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一般描述

丹参酮I是一种生物成分,属于从丹参中分离的丹参酮化合物。它通常用于扩张冠状动脉,增加冠状动脉血流量,调节诱变活性并保护心肌免受缺血。

应用

丹参酮I可用作分析参考标准品,用于通过不同的色谱技术对丹参和药物制剂中的分析物进行定量。
有关合适仪器技术的更多信息,请参考产品′s分析证书。如需进一步支持,请联系技术服务。

生化/生理作用

中药丹参(Salvia miltiorrhiza)中的菲醌成分。 通过调节粘附分子来调节或预防乳腺癌转移。抗炎症。

包装

无底玻璃瓶。内含物在插入的融合锥体内。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Development of the fingerprints for the quality of the roots of Salvia miltiorrhiza and its related preparations by HPLC-DAD and LC-MSn
Liu H-A, et al.
Journal of Chromatography. B, Biomedical Applications, 846(1-2), 32-41 (2007)
Simultaneous determination of cryptotanshinone, tanshinone I and tanshinone IIA in traditional Chinese medicinal preparations containing Radix salvia miltiorrhiza by HPLC
Shi Z, et al.
Journal of Pharmaceutical and Biomedical Analysis, 37(3), 481-486 (2005)
Ying Luo et al.
PloS one, 8(2), e56774-e56774 (2013-02-26)
We previously showed that tanshinone IIA ameliorated the hypoxia-induced pulmonary hypertension (HPH) partially by attenuating pulmonary artery remodeling. The hypoxia-induced proliferation of pulmonary artery smooth muscle cells (PASMCs) is one of the major causes for pulmonary arterial remodeling, therefore the
Wen-Quan Wang et al.
Journal of hematology & oncology, 5, 69-69 (2012-11-10)
Promotion of endothelial normalization restores tumor oxygenation and obstructs tumor cells invasion, intravasation, and metastasis. We therefore investigated whether a vasoactive drug, tanshinone IIA, could inhibit metastasis by inducing vascular normalization after palliative resection (PR) of hepatocellular carcinoma (HCC). A
Qing Cai et al.
Chinese journal of integrative medicine, 18(11), 837-845 (2012-10-23)
To investigate the protective effects of sodium tanshinone B (STB) on brain damage following focal ischemia-reperfusion (I/R) injury through interfering with N-methyl-D-aspartic acid receptor (NMDAR) and excitatory and inhibitory amino acids, and evaluate the potential mechanisms of the neuroprotective activity

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