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Merck

75047

Supelco

胡椒碱

analytical standard

别名:

1-胡椒酰哌啶

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About This Item

经验公式(希尔记法):
C17H19NO3
CAS号:
分子量:
285.34
Beilstein:
90741
EC號碼:
MDL號碼:
分類程式碼代碼:
85151701
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

化驗

≥97.0% (HPLC)

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

131-135 °C (lit.)

應用

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

格式

neat

儲存溫度

2-8°C

SMILES 字串

O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3

InChI

1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+

InChI 密鑰

MXXWOMGUGJBKIW-YPCIICBESA-N

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一般說明

Piperine is a naturally occurring bioactive alkaloid in pepper, which imparts pungency and bitter flavor to it. It has demonstrated health benefits and exhibits therapeutic properties, which include its role as an antimicrobial, antioxidant, antifungal, immunomodulatory and hepatoprotective agent. The inhibition of drug-metabolizing enzymes in hepatic and pulmonary tissues, and the enhancement of drug bioavailability by this compound are reported. It is also found to play an important role in reducing blood glucose, cholesterol and triglycerides.
Piperine is an amide isolated from the plant, Piper longum. It is a known inhibitor of hepatic and intestinal glucuronidation. Piperine is found to exhibit pharmacological properties like antitumor, antipyretic and anti-inflammatory activities.

應用

Piperine may be used as an analytical reference standard for the quantification of the analyte in:
  • Human plasma using high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS).
  • Piper nigrum extract using reversed phase high pressure liquid chromatographic method with UV detection (RP-HPLC-UV).
  • Food products using high-performance liquid chromatography with diode array detection (HPLC-DAD).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

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访问文档库

A liquid chromatography method for the simultaneous determination of curcumin and piperine in food products using diode array detection
Nagappan VK , et al.
Asian Journal of Research in Chemistry, 2(2), 115-118 (2009)
Preliminary study on inhibition of genotoxicity by piperine in mice
Selvendiran K, et al.
Fitoterapia, 76(3-4), 296-300 (2005)
Validated HPLC?MS/MS method for simultaneous determination of curcumin and piperine in human plasma
Wang M-X, et al.
Tropical Journal of Pharmaceutical Research, 11(4), 621-629 (2012)
Development and validation of rapid RP-HPLC method for estimation of piperine in Piper nigrum L
Upadhyay V, et al.
International Journal of Herbal Medicine, 1, 6-9 (2013)
Immunomodulatory and antitumor activity of Piper longum Linn. and piperine
Sunila.S.E and Kuttan.G
Journal of Ethnopharmacology, 90(2), 339- 346 (2004)

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