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等級
analytical standard
品質等級
化驗
≥97.0% (HPLC)
儲存期限
limited shelf life, expiry date on the label
技術
HPLC: suitable
gas chromatography (GC): suitable
mp
131-135 °C (lit.)
應用
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
格式
neat
儲存溫度
2-8°C
SMILES 字串
O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3
InChI
1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
InChI 密鑰
MXXWOMGUGJBKIW-YPCIICBESA-N
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一般說明
Piperine is a naturally occurring bioactive alkaloid in pepper, which imparts pungency and bitter flavor to it. It has demonstrated health benefits and exhibits therapeutic properties, which include its role as an antimicrobial, antioxidant, antifungal, immunomodulatory and hepatoprotective agent. The inhibition of drug-metabolizing enzymes in hepatic and pulmonary tissues, and the enhancement of drug bioavailability by this compound are reported. It is also found to play an important role in reducing blood glucose, cholesterol and triglycerides.
Piperine is an amide isolated from the plant, Piper longum. It is a known inhibitor of hepatic and intestinal glucuronidation. Piperine is found to exhibit pharmacological properties like antitumor, antipyretic and anti-inflammatory activities.
應用
Piperine may be used as an analytical reference standard for the quantification of the analyte in:
- Human plasma using high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS).
- Piper nigrum extract using reversed phase high pressure liquid chromatographic method with UV detection (RP-HPLC-UV).
- Food products using high-performance liquid chromatography with diode array detection (HPLC-DAD).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral - Aquatic Chronic 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
A liquid chromatography method for the simultaneous determination of curcumin and piperine in food products using diode array detection
Asian Journal of Research in Chemistry, 2(2), 115-118 (2009)
Preliminary study on inhibition of genotoxicity by piperine in mice
Fitoterapia, 76(3-4), 296-300 (2005)
Validated HPLC?MS/MS method for simultaneous determination of curcumin and piperine in human plasma
Tropical Journal of Pharmaceutical Research, 11(4), 621-629 (2012)
Development and validation of rapid RP-HPLC method for estimation of piperine in Piper nigrum L
International Journal of Herbal Medicine, 1, 6-9 (2013)
Immunomodulatory and antitumor activity of Piper longum Linn. and piperine
Journal of Ethnopharmacology, 90(2), 339- 346 (2004)
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