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Merck

74777

Millipore

黄芪甲苷IV

>98.0%

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About This Item

经验公式(希尔记法):
C41H68O14
CAS号:
分子量:
784.97
MDL编号:
UNSPSC代码:
41106200
PubChem化学物质编号:
NACRES:
NA.85

质量水平

方案

≥98.0% (TLC)
>98.0%

表单

powder

mp

295-296 °C (lit.)

SMILES字符串

CC(C)(O)[C@@H]1CC[C@@](C)(O1)[C@H]2[C@@H](O)C[C@@]3(C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H]6C(C)(C)[C@H](CC[C@@]67C[C@@]47CC[C@]23C)O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O

InChI

1S/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1

InChI key

QMNWISYXSJWHRY-YLNUDOOFSA-N

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生化/生理作用

抗炎。

其他说明

黄芪的化学成分

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Dingkun Gui et al.
PloS one, 7(6), e39824-e39824 (2012-06-30)
Glucose-induced reactive oxygen species (ROS) production initiates podocyte apoptosis, which represents a novel early mechanism leading to diabetic nephropathy (DN). Here, we tested the hypothesis that Astragaloside IV(AS-IV) exerts antioxidant and antiapoptotic effects on podocytes under diabetic conditions. Apoptosis, albuminuria
Ming Hao et al.
Zhonghua yi xue za zhi, 92(30), 2104-2107 (2012-11-20)
To explore the protective effects of astragaloside IV on retinal ganglion cells (RGC) incubated under high glucose. Cultured RGC-5 were divided into 3 groups: control, high glucose and high glucose+astragaloside IV. The survival rate of cell was measured by CCK-8
Wenya Shan et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(1), 85-88 (2012-06-30)
To provide a scientific basis for the drug-combination and aim to examine whether astragaloside IV has the impact on the cytochrome P450 enzymes. Tolbutamide, chlorzoxazone, coumarin, nifedipine, and phenacetin were as probe substrates of rat CYP2C9, CYP2E1, CYP2A6, CYP3A4, and
I. Kitagawa et al.
Chemical & Pharmaceutical Bulletin, 31, 698-698 (1983)
Min Li et al.
Neurochemistry international, 60(5), 458-465 (2012-02-22)
Inflammation injury plays a key role in the process of cerebral injury induced by ischemia/reperfusion (I/R). Thus, we studied the potential of astragaloside IV, one of the major and active components of the astragalus membranaceous, to protect rat against cerebral

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