MABT332

Anti-Obscurin Antibody, clone 4A8

clone 4A8, from mouse

• 别名: Obscurin, Obscurin-RhoGEF, Obscurin-myosin light chain kinase, Obscurin-MLCK
• UNSPSC代码: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物来源: mouse
• 抗体形式: purified antibody
• 抗体产品类型: primary antibodies
• 克隆: 4A8, monoclonal
• 种属反应性: rat
• 种属反应性（根据同源性预测）: human (based on 100% sequence homology)
• 技术: immunohistochemistry: suitable (paraffin); western blot: suitable
• 同位素/亚型: IgG1κ
• NCBI登记号: NP_001092093
• UniProt登记号: Q5VST9
• 运输: wet ice
• 靶向翻译后修饰: unmodified
• 基因信息: human ... OBSCN(84033)

说明

一般描述

Obscurin, also known as Obscurin-RhoGEF or Obscurin-myosin light chain kinase, is encoded by the gene name OBSCN. Obscurin is involved in myofibrillogenesis and the assembly of myosin into sarcomeric A bands in striated muscle. Obscurin isoform 3 plus ANK1 isoform Mu17/Ank1.5 may be molecular link between the sarcoplasmic reticulum and myofibrils.

免疫原

GST-tagged recombinant protein corresponding to the N-terminus of human Obscurin.

应用

This Anti-Obscurin antibody is validated for use in WB, IH(P) for the detection of Obscurin.

Western Blotting Analysis: A representative lot detected Obscurin in extracts of adult rat quadriceps tissue lysate (Bowman, A.L., et al. (2007). FEBS Letters. 581:1549-1554).
Immunohistochemistry by fluorescent Analysis: A representative lot detected Isocitrate dehydrogenase in rat muscle tissue at resting stage (Bowman, A.L., et al. (2007). FEBS Letters. 581:1549-1554).

质量

Evaluated by Immunohistochemistry in rat skeletal muscle tissue.

Immunohistochemistry Analysis: A 1:250 dilution of this antibody detected Obscurin in rat skeletal muscle tissue.

目标描述

800 kDa calculated

外形

Format: Purified

其他说明

Concentration: Please refer to lot specific datasheet.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable