OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms:
ARHGEF30, UNC89
Species:
Human OBSCN (84033), Mouse Obscn (380698), Rat Obscn (338458), sheep OBSCN (101121853), naked mole-rat Obscn (101701039), Zebrafish obscn (445358), chicken OBSCN (420395), dog OBSCN (482206), domestic cat OBSCN (101101539), cow OBSCN (537193)
UniProtKB ID:
Gene ID:
- Human(84033) Summary: The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 720 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin, and may have a role in the organization of myofibrils during assembly and may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(380698) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- Rat(338458) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- sheep(101121853) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- naked mole-rat(101701039) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- Zebrafish(445358) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- chicken(420395) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- dog(482206) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- domestic cat(101101539) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- cow(537193) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- domestic guinea pig(100727808) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Obscurin Antibody, clone 5H10A, clone 5H10A, from mouse,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-OBSCN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-OBSCN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-C1ORF145 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry