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Merck
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文件

MAB4343

Sigma-Aldrich

抗SOX-2抗体

clone 6F1.2, Chemicon®, from mouse

别名:

Anti-ANOP3, Anti-MCOPS3

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

100

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

6F1.2, monoclonal

物種活性

mouse, human

包裝

antibody small pack of 25 μg

製造商／商標名

Chemicon®

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

輸入

sample type: mouse embryonic stem cell(s)
sample type neural stem cell(s)
sample type: human embryonic stem cell(s)
sample type induced pluripotent stem cell(s)

同型

IgG2b

NCBI登錄號

NM_003106.2

UniProt登錄號

P48431

運輸包裝

ambient

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... SOX2(6657)
mouse ... Sox2(20674)

相关类别

一般說明

Sox-2在胚胎干细胞发育中起关键作用，并已表明它可以帮助干细胞保持多能性。它也被证明可与正在发育的中枢神经系统中自由分裂干细胞和前体细胞有关。

免疫原

重组GST融合蛋白。

應用

抗SOX-2抗体可检测SOX-2水平 & 已出版&并经过验证可用于IC、IH和&WB。
研究子类别
转录因子
研究类别
表观遗传学&核功能

品質

已经过测试

標靶描述

~34 kDa

外觀

已通过蛋白A亲和色谱纯化的免疫球蛋白，以液体形式溶于0.02 M磷酸盐缓冲液（pH 7.6）和0.25 M NaCl中。包含0.1％叠氮化钠。
形式：纯化

儲存和穩定性

以未稀释的等分形式可在2-8°C冷藏保存长达12个月。

其他說明

浓度：请参考批次特异性浓缩物的分析证书。

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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Masoumeh Fakhr Taha et al.
BioMed research international, 2014, 941486-941486 (2014-08-26)
The expression pattern of pluripotency markers in adipose tissue-derived stem cells (ADSCs) is a subject of controversy. Moreover, there is no data about the signaling molecules that regulate these markers in ADSCs. In the present study, we studied the roles
Valentina Poletti et al.
PloS one, 10(5), e0126590-e0126590 (2015-05-16)
Genome-wide mapping of transcriptional regulatory elements is an essential tool for understanding the molecular events orchestrating self-renewal, commitment and differentiation of stem cells. We combined high-throughput identification of transcription start sites with genome-wide profiling of histones modifications to map active
High-content imaging-based screening of microenvironment-induced changes to stem cells.
Vega, SL; Liu, E; Patel, PJ; Kulesa, AB; Carlson, AL; Ma, Y; Becker, ML; Moghe, PV
Journal of Biomolecular Screening null
Weixiang Guo et al.
Nature protocols, 7(11), 2005-2012 (2012-10-20)
In adult mammals, the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone of the dentate gyrus (DG) show ongoing neurogenesis, and multipotent neural stem or progenitor cells (NSCs) in these two regions exhibit different intrinsic properties. However
Ying Li et al.
Scientific reports, 6, 38665-38665 (2016-12-08)
Notch1 signaling plays a critical role in maintaining and determining neural stem/progenitor cell (NSPC) fate, yet the transcriptional mechanism controlling Notch1 specific expression in NSPCs remains incomplete. Here, we show transcription factor Nkx6.1 interacts with a cis-element (CR2, an evolutionarily
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