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Merck
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主要文件

MAB1919

Sigma-Aldrich

抗原纤蛋白抗体,克隆11C1.3

clone 11C1.3, Chemicon®, from mouse

别名:

Anti-ACMICD, Anti-FBN, Anti-GPHYSD2, Anti-MASS, Anti-MFLS, Anti-MFS1, Anti-OCTD, Anti-SGS, Anti-SSKS, Anti-WMS, Anti-WMS2

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

11C1.3, monoclonal

物種活性

bovine, pig, human

製造商/商標名

Chemicon®

技術

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG1κ

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... FBN1(2200)

相关类别

特異性

牛带状原纤维。与人弹性蛋白微原纤维反应良好,可用于马凡氏患者或从这些患者获得的成纤维细胞中研究这些原纤维的存在和组织。

免疫原

牛带状原纤维

應用

免疫印迹:抗体与牛主动脉平滑肌细胞释放的35万Da蛋白反应,该蛋白与原纤维蛋白相同。

免疫组化:新鲜冷冻组织:1:200-1:500。石蜡切片经微波柠檬酸盐缓冲液抗原提取后有反应。

免疫沉淀:5微升抗体稀释在不超过400微升的牛平滑肌细胞浓缩上清液中。我们建议使用抗小鼠IgG抗体头或兔抗小鼠捕获抗体,然后使用蛋白A。A.

ELISA

最佳稀释度必须由最终用户确定。
抗纤原蛋白抗体,克隆11C1.3是用于ELISA、IF、IP、WB、IH(P)的抗纤原蛋白抗体。
研究子类别
ECM 蛋白
研究类别
细胞结构

外觀

形式:纯化
液体

儲存和穩定性

以未稀释的等分试样保存于-20°C下12个月。应避免反复冻/融循环。

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Mohamed A Sideek et al.
Matrix biology : journal of the International Society for Matrix Biology, 34, 114-123 (2013-10-24)
Latent transforming growth factor-beta-1 binding protein-2 (LTBP-2) is a protein of ill-defined function associated with elastic fibers during elastinogenesis. Although LTBP-2 binds fibrillin-1, fibulin-5, and heparin/heparan sulfate, molecules critical for normal elastic fiber assembly, it does not interact directly with
F Wang et al.
The British journal of dermatology, 173(6), 1420-1430 (2015-07-17)
Striae gravidarum (SG), or 'stretch marks' of pregnancy, begin as erythematous streaks, and mature over months to years to become permanent scar-like bands that may be hypopigmented, atrophic and lax. To investigate early molecular alterations that may promote laxity of
Eric Hanssen et al.
The Journal of biological chemistry, 279(28), 29185-29194 (2004-05-08)
The interactions of microfibril-associated glycoprotein (MAGP)-2 have been investigated with fibrillins and fibrillin-containing microfibrils. Solid phase binding assays were conducted with recombinant fragments covering fibrillin-1 and most of fibrillin-2. MAGP-2, and its structure relative MAGP-1, were found to bind two
A common variant rs2054564 in ADAMST17 is associated with susceptibility to lumbar spondylosis.
Taniguchi, et al.
Scientific Reports, 13, 4900-4900 (2023)
ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.
Kutz, WE; Wang, LW; Bader, HL; Majors, AK; Iwata, K; Traboulsi, EI; Sakai, LY; Keene, DR; Apte, SS
The Journal of Biological Chemistry null

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