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Merck
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主要文件

FCMAB390F

Sigma-Aldrich

Milli-Mark® Anti-pan Histone-FITC Antibody, clone H11-4

clone H11-4, Milli-Mark®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

共軛

FITC conjugate

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

H11-4, monoclonal

物種活性

human

製造商/商標名

Milli-Mark®

技術

flow cytometry: suitable

同型

IgG1

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... H3C1(8350)

一般說明

There are 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. The five major classes of histones are H1/H5, H2A, H2B, H3, and H4. Histones H2A, H2B, H3 and H4 are known as the core histones, while histones H1 and H5 are known as the linker histones. Histones feature a main globular domain and a long N terminal tail which are involved with the structure of the nucleosomes of the ′beads on a string′ structure. They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation.

特異性

Due to the highly conserved nature of histones, this antibody is predicted to have wide species reactivity.

應用

This Milli-Mark Anti-pan Histone-FITC Antibody, clone H11-4 is validated for use in FC for the detection of pan Histone.

品質

Evaluated by flow cytometry using HeLa cells.

標靶描述

Antibody recognizes histones H1, H2A, H2B, H3, and H4. Calculated molecular weight for these histones range from 14 to 21 kDa

法律資訊

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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