推荐产品
生物源
rabbit
品質等級
共軛
ALEXA FLUOR™ 488
無性繁殖
polyclonal
物種活性
mouse, rat
製造商／商標名
Neuro-Chrom
技術
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
運輸包裝
wet ice
目標翻譯後修改
unmodified
一般說明
Antibodies to neuronal proteins have become critical tools for identifying neurons and discerning morphological characteristics in culture and complex tissue. While the labeling from classic histological techniques such as Golgi staining and modern molecular approaches such as GFP constructs yield excellent cytoarchitectural detail, these approaches are technically challenging and impractical for many neuroscience research needs. Neuron-specific antibodies are convenient precision tools useful in revealing cytoarchitecture, but are limited to the protein target distribution within the neuron, which may differ greatly from nucleus to soma to dendrite and axon. To achieve as complete a morphological staining as possible across all parts of neurons, Millipore has developed a polyclonal antibody blend that reacts against key somatic, nuclear, dendritic, and axonal proteins distributed across the pan-neuronal architecture that can then be detected by a single secondary antibody. This antibody cocktail has been validated in diverse methods, cell culture and immuno-histochemistry, giving researchers a convenient and specific qualitative and quantitative tool for studying neuronal morphology.
特異性
Cat. # ABN2300A4 is specific to axons (neurites), dendrites, nucleus, and the cell body of neurons.
Reactivity with other species has not been determined.
免疫原
Epitope: Whole Neuron Marker
應用
Neuro-Chrom Pan Neuronal Marker-Rabbit, Alexa488 conjugate is an antibody targeting the Pan Neuronal Marker protein, validated for use in ICC, IHC & IF.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
品質
Routinely tested Rat E18 cortex primary neurons in Immunocytochemistry.
外觀
Polyclonal antibody cocktail blend conjugated to Alexa Fluor™ 488 in PBS buffer with 15mg/mL BSA and 0.05% NaN3
儲存和穩定性
Maintain at 2-8°C for up to 1 year from date of receipt.
分析報告
Control
Rat E18 cortex primary neuron cell culture or mouse adult brain cryosections.
Rat E18 cortex primary neuron cell culture or mouse adult brain cryosections.
法律資訊
ALEXA FLUOR is a trademark of Life Technologies
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Xinhua Zhan et al.
Neurology, 87(22), 2324-2332 (2016-10-28)
We determined whether Gram-negative bacterial molecules are associated with Alzheimer disease (AD) neuropathology given that previous studies demonstrate Gram-negative Escherichia coli bacteria can form extracellular amyloid and Gram-negative bacteria have been reported as the predominant bacteria found in normal human
Andreas C Woerner et al.
Science (New York, N.Y.), 351(6269), 173-176 (2015-12-05)
Amyloid-like protein aggregation is associated with neurodegeneration and other pathologies. The nature of the toxic aggregate species and their mechanism of action remain elusive. Here, we analyzed the compartment specificity of aggregate toxicity using artificial β-sheet proteins, as well as
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