推荐产品
![聚[(9,9-二正辛基芴基-2,7-二基)-alt-(苯并[2,1,3]噻二唑-4,8-二基)] average Mn ≤25000](/deepweb/assets/sigmaaldrich/product/structures/428/661/1c4ebb98-9d51-48c0-96c7-e556ca425aa4/640/1c4ebb98-9d51-48c0-96c7-e556ca425aa4.png)
生物源
rabbit
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
human
技術
ChIP: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... MSL3(10943)
一般說明
MSL3, also known as Male-specific lethal 3 homolog, or Male-specific lethal-3 homolog 1, or Male-specific lethal-3 protein-like 1 (MSL3-like 1), and encoded by the gene MSL3/MSL3L1, is a component of the MSL(male-specific lethal ) histone acetyltransferase complex which is responsible for the majority of histone H4 acetylation at ′Lys-16′ which is implicated in the formation of higher-order chromatin structure. MSL3 may also be involved in chromatin remodeling and transcriptional regulation. Additionally, MSL3 may have a role in X inactivation as its gene is a target for X inactivation. MSL3 is localized to the nucleus. MSL3 is expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart.
免疫原
Linear peptide corresponding to human MSL3-like 1.
應用
Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated MSL3-like 1 from HeLa cell lysate (Wu, L., et al. (2011). Mol Cell. 43(1):132-144.).
Detect MSL3-like 1 using this Anti-MSL3-like 1 antibody validated for use in western blotting & ChIP.
品質
Evaluated by Western Blotting in Jurkat cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected MSL3-like 1 in 10 µg of Jurkat cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected MSL3-like 1 in 10 µg of Jurkat cell lysate.
標靶描述
~58 kDa observed. Five isoforms are known to exist at 60 kDa (isoform 1), 53 kDa (isoform 2), 58 kDa (isoform 3), 40 kDa (isoform 4), and 48 kDa (isoform 5).
外觀
Format: Purified
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
未找到合适的产品？
试试我们的产品选型工具.
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Zeliha Yalçin et al.
Nature communications, 15(1), 5032-5032 (2024-06-13)
Maintenance of genome integrity requires tight control of DNA damage response (DDR) signalling and repair, with phosphorylation and ubiquitination representing key elements. How these events are coordinated to achieve productive DNA repair remains elusive. Here we identify the ubiquitin-conjugating enzyme
Debosree Pal et al.
Nature structural & molecular biology, 30(7), 935-947 (2023-06-13)
Mammalian genomes harbor abundant transposable elements (TEs) and their remnants, with numerous epigenetic repression mechanisms enacted to silence TE transcription. However, TEs are upregulated during early development, neuronal lineage, and cancers, although the epigenetic factors contributing to the transcription of
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门