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Merck
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文件

AB3538P

Sigma-Aldrich

抗单羧酸转运蛋白1抗体

Chemicon®, from rabbit

别名:

MCT1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human

製造商/商標名

Chemicon®

技術

ELISA: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... SLC16A1(6566)

特異性

可识别人单羧酸转运蛋白1(MCT1)。免疫原与MCT2-8没有明显的序列同源性。

免疫原

人MCT1 C末端附近的15个氨基酸肽序列(Gerhart et al. 1997; Knott et al. 1999; Takanaga et al. 1995; Carpenter et al. 1996; Koehler-Stec et al. 1998; Yoon et al. 1999; Halestrap & Price 1999)。

應用

研究子类别
离子通道 & 转运体
研究类别
神经科学
蛋白质印迹:使用ECL为1-5μg/mL
ELISA:1:10,000-1:100,000,每孔使用50-100 ng对照肽。
最佳工作稀释度必须由最终用户进行确定。
该抗单羧酸转运蛋白1抗体经验证可用于ELISA,WB检测单羧酸转运蛋白1。

外觀

亲和纯化的免疫球蛋白。 含0.1%BSA的PBS液体。

儲存和穩定性

收到货后,在-20°C下以未稀释等分试样可保存长达6个月。应避免反复冻/融循环。

其他說明

浓度:请参考批次特异性浓缩物的分析证书。

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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Expression of monocarboxylate transporters 1, 2, and 4 in human tumours and their association with CD147 and CD44.
Pinheiro, C; Reis, RM; Ricardo, S; Longatto-Filho, A; Schmitt, F; Baltazar, F
Journal of Biomedicine and Biotechnology null
Chun-Kai Huang et al.
Nature communications, 8, 14706-14706 (2017-03-11)
Adipocytes are the most abundant stromal partners in breast tissue. However, the crosstalk between breast cancer cells and adipocytes has been given less attention compared to cancer-associated fibroblasts. Here we find, through systematic screening, that primary mammary gland-derived adipocytes (MGDAs)
S-Nitrosation of monocarboxylate transporter 1: inhibition of pyruvate-fueled respiration and proliferation of breast cancer cells.
Diers, AR; Broniowska, KA; Chang, CF; Hill, RB; Hogg, N
Free radical biology & medicine null
Eduardo C A Silva et al.
Oncotarget, 9(29), 20386-20398 (2018-05-15)
Metabolic reprogramming is one of the hallmarks of cancer. The hyperglycolytic phenotype is often associated with the overexpression of metabolism-associated proteins, such as monocarboxylate transporters (MCTs). MCTs are little explored in germ cell tumors (GCTs), thus, the opportunity to understand
Julieta Afonso et al.
Cell cycle (Georgetown, Tex.), 15(3), 368-380 (2015-12-05)
Monocarboxylate transporters (MCTs) are vital for intracellular pH homeostasis by extruding lactate from highly glycolytic cells. These molecules are key players of the metabolic reprogramming of cancer cells, and evidence indicates a potential contribution in urothelial bladder cancer (UBC) aggressiveness

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