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Merck
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主要文件

8.55129

Sigma-Aldrich

NovaSyn® TG PAP RESIN

Novabiochem®

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About This Item

质量水平

产品线

NovaSyn® TG
Novabiochem®

表单

beads

反应适用性

reaction type: Fmoc solid-phase peptide synthesis

制造商/商品名称

Novabiochem®

应用

peptide synthesis

官能团

amine

储存温度

2-8°C

一般描述

NovaSyn TG PAP resin contains an acid cleavable linkage between the polystyrene matrix and the PEG chain. Treatment of peptides prepared on this resin with TFA/thioanisole (95:5) for 12 hours or TMSBr/TFA/thioanisole (1:94:5) for 60 minutes releases a fully deprotected peptide possessing a PEG-chain attached to the C-terminus [1]. Such peptide-PEG conjugates can be used directly as immunogens, without the need for a carrier protein. The peptide-PEG conjugates are also highly soluble and provide an effective solution to insoluble peptides.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references

[1] W. Rapp in ′Combinatorial Peptide and Nonpeptide Libraries′, G. Jung (Eds), Vch, 1996, pp. 425.

分析说明

Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result

法律信息

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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